Shields J A, Shields C L, Eagle R C, Barrett J, De Potter P
Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Retina. 1995;15(3):213-9.
Among conditions that can simulate retinoblastoma, endogenous endophthalmitis is quite rare.
Case records of six children with unusual forms of endogenous endophthalmitis, all of whom were referred to the authors because retinoblastoma was a strong diagnostic consideration, were reviewed. The clinical features that may help differentiate atypical endophthalmitis from retinoblastoma were investigated.
The final diagnosis in these cases included idiopathic subretinal abscess, streptococcal endophthalmitis, idiopathic retinovitreal abscess, cytomegalovirus endophthalmitis, Candida endophthalmitis, and meningococcal endophthalmitis. All of the affected children presented primarily with ocular findings without serious systemic infection. Although these conditions closely simulated retinoblastoma, they were more likely to have signs of concurrent or prior inflammation.
Differentiation between infectious conditions and retinoblastoma can sometimes be difficult, but clues as to the diagnosis can be obtained from careful clinical examination.
在可模拟视网膜母细胞瘤的病症中，内源性眼内炎相当罕见。
回顾了6例患有不寻常形式内源性眼内炎儿童的病例记录，所有这些儿童均因视网膜母细胞瘤是一个重要的诊断考虑因素而被转诊至作者处。研究了可能有助于将非典型眼内炎与视网膜母细胞瘤区分开来的临床特征。
这些病例的最终诊断包括特发性视网膜下脓肿、链球菌性眼内炎、特发性视网膜玻璃体脓肿、巨细胞病毒性眼内炎、念珠菌性眼内炎和脑膜炎球菌性眼内炎。所有受影响的儿童主要表现为眼部症状，无严重的全身感染。尽管这些病症与视网膜母细胞瘤极为相似，但它们更可能有并发或先前炎症的迹象。
感染性病症与视网膜母细胞瘤之间的鉴别有时可能很困难，但通过仔细的临床检查可以获得诊断线索。
