Armstrong N, Balding J, Gentle P, Kirby B
School of Education, University of Exeter, UK.
Br J Sports Med. 1990 Mar;24(1):61-6. doi: 10.1136/bjsm.24.1.61.
Surveys from several countries have identified the presence of risk factors known to be associated with coronary heart disease in children. Data on the distribution of coronary risk factor variables in British children are scarce. This study was therefore designed to test the feasibility of collecting coronary risk factor data from British children and to conduct a preliminary examination of the problem. One hundred and seven children (mean age 12.8 yr) had their height, weight, triceps skinfold and blood pressure checked. Blood samples for cholesterol and HDL-cholesterol analysis were obtained from 93 children. Peak VO2 was determined on 48 children, 76 children had their daily activity monitored and 59 children's stage of sexual maturity was assessed. The boys' peak VO2 was significantly higher than the girls, whether expressed in l.min-1 (p less than 0.05) or ml.kg.-1min-1 (p less than 0.01). No other significant differences (p greater than 0.05) between the sexes were detected. The results indicate that children have relatively high serum cholesterol levels (boys 4.58 +/- 0.79; girls 4.72 +/- 0.80 mmol.l-1). The willingness and enthusiasm of the children, parents and schools to take part in the study clearly demonstrated the feasibility of a large scale study being successfully pursued in the United Kingdom.
来自几个国家的调查已经确定，在儿童中存在已知与冠心病相关的风险因素。关于英国儿童冠心病风险因素变量分布的数据很少。因此，本研究旨在测试从英国儿童中收集冠心病风险因素数据的可行性，并对该问题进行初步检查。对107名儿童（平均年龄12.8岁）进行了身高、体重、肱三头肌皮褶厚度和血压检查。从93名儿童中采集了用于胆固醇和高密度脂蛋白胆固醇分析的血样。对48名儿童测定了最大摄氧量，对76名儿童的日常活动进行了监测，并对59名儿童的性成熟阶段进行了评估。男孩的最大摄氧量显著高于女孩，无论是以升/分钟（p<0.05）还是毫升/千克·分钟（p<0.01）表示。未检测到两性之间的其他显著差异（p>0.05）。结果表明，儿童的血清胆固醇水平相对较高（男孩4.58±0.79；女孩4.72±0.80毫摩尔/升）。儿童、家长和学校参与研究的意愿和热情清楚地表明了在英国成功开展大规模研究的可行性。
