Institute for Global Health, University College London, London, UK.
Int J Epidemiol. 2013 Apr;42(2):520-32. doi: 10.1093/ije/dyt012. Epub 2013 Mar 18.
Progress towards the Millennium Development Goals (MDGs) has been uneven. Inequalities in child health are large and effective interventions rarely reach the most in need. Little is known about how to reduce these inequalities. We describe and explain the equity impact of a women's group intervention in India that strongly reduced the neonatal mortality rate (NMR) in a cluster-randomised trial. We conducted secondary analyses of the trial data, obtained through prospective surveillance of a population of 228,186. The intervention effects were estimated separately, through random effects logistic regression, for the most and less socio-economically marginalised groups. Among the most marginalised, the NMR was 59% lower in intervention than in control clusters in years 2 and 3 (70%, year 3); among the less marginalised, the NMR was 36% lower (35%, year 3). The intervention effect was stronger among the most than among the less marginalised (P-value for difference = 0.028, years 2-3; P-value for difference = 0.009, year 3). The stronger effect was concentrated in winter, particularly for early NMR. There was no effect on the use of health-care services in either group, and improvements in home care were comparable. Participatory community interventions can substantially reduce socio-economic inequalities in neonatal mortality and contribute to an equitable achievement of the unfinished MDG agenda.
千年发展目标(MDGs)的进展参差不齐。儿童健康方面的不平等现象很大,有效的干预措施很少能惠及最需要的人群。对于如何减少这些不平等现象,我们知之甚少。我们描述并解释了印度一个妇女团体干预措施对公平性的影响,该干预措施在一项集群随机试验中大大降低了新生儿死亡率(NMR)。我们通过对一个由 228186 人组成的人群进行前瞻性监测获得了该试验的数据,并对其进行了二次分析。我们通过随机效应逻辑回归分别为最边缘和较不边缘的社会经济群体估计干预效果。在最边缘的群体中,干预组在第 2 年和第 3 年的 NMR 比对照组低 59%(第 3 年为 70%);在较不边缘的群体中,NMR 低 36%(第 3 年为 35%)。干预效果在最边缘的群体中比在较不边缘的群体中更强(差异的 P 值=0.028,第 2-3 年;差异的 P 值=0.009,第 3 年)。这种更强的效果主要集中在冬季,特别是对早期 NMR 的效果更为明显。该干预措施对两组的医疗服务利用均没有影响,家庭护理的改善情况相当。参与式社区干预可以大大减少新生儿死亡率方面的社会经济不平等,有助于公平地实现未完成的 MDG 议程。