Department of Dermatology, Coimbra University Hospital, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal.
Contact Dermatitis. 2013 Apr;68(4):239-43. doi: 10.1111/cod.12037.
In order to establish a consensus recommendation for performing photopatch testing, a photopatch test taskforce group was established under the joint umbrella of the European Society for Contact Dermatitis and the European Society for Photodermatology in 2000. After proposing the most adequate methodology in 2004 and completing a European multicentre photopatch test study in 2011, this taskforce is recommending a list of photoallergens that should form part of a baseline series for photopatch testing in Europe. It contains mainly ultraviolet filters and drugs, mostly non-steroidal anti-inflammatory drugs. The choice of chemicals was based on the results of a recent multicentre study, previous published cases of photoallergy, and use of the substances in the European market. It is suggested that an extended list of photoallergens should be photopatch tested in selected cases, along with patients' own products. Two contact allergens, cinnamyl alcohol and decyl glucoside, should be simultaneously patch tested in order to clarify photopatch and patch test reactions, respectively, to ketoprofen and methylene bis-benzotriazolyl tetramethylbutylphenol (Tinosorb M™).
为了制定进行光变应原检测的共识性推荐建议，一个光变应原检测特别工作组于 2000 年在欧洲接触性皮炎学会和欧洲光皮科学会的联合支持下成立。在 2004 年提出最合适的方法学之后，并于 2011 年完成了一项欧洲多中心光变应原检测研究，该工作组建议了一份应该纳入欧洲光变应原检测基本系列的光变应原清单。它主要包含紫外线滤光剂和药物，主要是非甾体类抗炎药。化学物质的选择基于最近一项多中心研究的结果、以前发表的光变应原病例以及这些物质在欧洲市场的使用情况。建议在选定的病例中，对光变应原检测进行扩展清单检测，并结合患者自身的产品。两种接触变应原，肉桂醇和癸基葡萄糖苷，应该同时进行斑贴试验，以分别阐明酮洛芬和亚甲基双-苯并三唑基四甲基丁基苯酚（Tinosorb M™）的光变应原和斑贴试验反应。
