School of Medicine, University Center of Espírito Santo, Colatina, Brazil.
Int J Gen Med. 2013;6:57-66. doi: 10.2147/IJGM.S41480. Epub 2013 Mar 5.
To correlate cardiovascular risk factors (e.g., hypertension, obesity, hypercholesterolemia, hypertriglyceridemia, hyperglycemia, sedentariness) in childhood and adolescence with the occurrence of cardiovascular disease.
A systematic review of books and selected articles from PubMed, SciELO and Cochrane from 1992 to 2012.
Risk factors for atherosclerosis are present in childhood, although cardiovascular disease arises during adulthood. This article presents the main studies that describe the importance of investigating the risk factors for cardiovascular diseases in childhood and their associations. Significant rates of hypertension, obesity, dyslipidemia, and sedentariness occur in children and adolescents. Blood pressure needs to be measured in childhood. An increase in arterial blood pressure in young people predicts hypertension in adulthood. The death rate from cardiovascular disease is lowest in children with lower cholesterol levels and in individuals who exercise regularly. In addition, there is a high prevalence of sedentariness in children and adolescents.
Studies involving the analysis of cardiovascular risk factors should always report the prevalence of these factors and their correlations during childhood because these factors are indispensable for identifying an at-risk population. The identification of risk factors in asymptomatic children could contribute to a decrease in cardiovascular disease, preventing such diseases as hypertension, obesity, and dyslipidemia from becoming the epidemics of this century.
分析儿童和青少年时期的心血管危险因素(如高血压、肥胖、高胆固醇血症、高三酰甘油血症、高血糖症、久坐不动)与心血管疾病发生之间的相关性。
对 1992 年至 2012 年期间PubMed、SciELO 和 Cochrane 中书籍和精选文章进行的系统评价。
动脉粥样硬化的危险因素存在于儿童时期,尽管心血管疾病发生在成年期。本文介绍了描述在儿童时期调查心血管疾病危险因素及其相关性的重要研究。儿童和青少年中高血压、肥胖、血脂异常和久坐不动的发生率显著。儿童时期需要测量血压。年轻人的动脉血压升高预示着成年期高血压。胆固醇水平较低和经常运动的人死于心血管疾病的风险最低。此外,儿童和青少年中久坐不动的发生率很高。
涉及心血管危险因素分析的研究应始终报告这些因素在儿童时期的流行情况及其相关性,因为这些因素是确定高危人群所必需的。在无症状儿童中识别危险因素有助于降低心血管疾病的发生,防止高血压、肥胖和血脂异常等疾病成为本世纪的流行病。