Wang Hao, Coppola Marco, Robinson Richard D, Scribner James T, Vithalani Veer, de Moor Carrie E, Gandhi Raj R, Burton Mandy, Delaney Kathleen A
Department of Emergency Medicine, JPS Health Network, 1500 S. Main St. Fort Worth, TX 76104, USA.
J Clin Med Res. 2013 Apr;5(2):75-83. doi: 10.4021/jocmr1227w. Epub 2013 Feb 25.
It has been found that significantly different clinical outcomes occur in trauma patients with different mechanisms of injury. Ground level falls (GLF) are usually considered "minor trauma" with less injury occurred in general. However, it is not uncommon that geriatric trauma patients sustain cervical spine (C-spine) fractures with other associated injuries due to GLF or less. The aim of this study is to determine the injury patterns and the roles of clinical risk factors in these geriatric trauma patients.
Data were reviewed from the institutional trauma registry of our local level 1 trauma center. All patients had sustained C-spine fracture(s). Basic clinical characteristics, the distribution of C-spine fracture(s), and mechanism of injury in geriatric patients (65 years or older) were compared with those less than 65 years old. Furthermore, different clinical variables including age, gender, Glasgow coma scale (GCS), blood alcohol level, and co-existing injuries were analyzed by multivariate logistic regression in geriatric trauma patients due to GLF and internally validated by random bootstrapping technique.
From 2006 - 2010, a total of 12,805 trauma patients were included in trauma registry, of which 726 (5.67%) had sustained C-spine fracture(s). Among all C-spine fracture patients, 19.15% (139/726) were geriatric patients. Of these geriatric patients 27.34% (38/139) and 53.96% (75/139) had C1 and C2 fractures compared with 13.63% (80/587) and 21.98% (129/587) in young trauma patients (P < 0.001). Of geriatric trauma patients 13.67% (19/139) and 18.71% (26/139) had C6 and C7 fractures compared with 32.03% (188/587) and 41.40% (243/587) in younger ones separately (P < 0.001). Furthermore, 53.96% (75/139) geriatric patients had sustained C-spine fractures due to GLF with more upper C-spine fractures (C1 and C2). Only 3.2% of those had positive blood alcohol levels compared with 52.9% of younger patients (P < 0.001). In addition, 6.34% of geriatric patients due to GLF had intracranial pathology (ICP) which was one of the most common co-injuries with C-spine fractures. Logistic regression analysis showed the adjusted odds ratios of 1.17 (age) and 91.57 (male) in geriatric GLF patients to predict this co-injury pattern of C-spine fracture and ICP.
Geriatric patients tend to sustain more upper C-spine fractures than non-geriatric patients regardless of the mechanisms. GLF or less not only can cause isolated C-spines fracture(s) but also lead to other significant injuries with ICP as the most common one in geriatric patients. Advanced age and male are two risk factors that can predict this co-injury pattern. In addition, it seems that alcohol plays no role in the cause of GLF in geriatric trauma patients.
研究发现,创伤机制不同的创伤患者临床结局存在显著差异。平地跌倒(GLF)通常被视为“轻度创伤”,一般受伤程度较轻。然而,老年创伤患者因平地跌倒或程度更轻的情况而发生颈椎(C 型脊柱)骨折并伴有其他相关损伤的情况并不少见。本研究的目的是确定这些老年创伤患者的损伤模式以及临床危险因素的作用。
回顾了我们当地一级创伤中心机构创伤登记处的数据。所有患者均发生了 C 型脊柱骨折。将老年患者(65 岁及以上)的基本临床特征、C 型脊柱骨折的分布情况以及损伤机制与 65 岁以下的患者进行了比较。此外,对老年创伤患者因平地跌倒导致的不同临床变量,包括年龄、性别、格拉斯哥昏迷量表(GCS)、血液酒精水平和并存损伤,进行了多因素逻辑回归分析,并通过随机自抽样技术进行内部验证。
2006 年至 2010 年期间,创伤登记处共纳入 12,805 例创伤患者,其中 726 例(5.67%)发生了 C 型脊柱骨折。在所有 C 型脊柱骨折患者中,19.15%(139/726)为老年患者。在这些老年患者中,27.34%(38/139)和 53.96%(75/139)发生了 C1 和 C2 骨折,而年轻创伤患者中这一比例分别为 13.63%(80/587)和 21.98%(129/587)(P < 0.001)。老年创伤患者中,13.67%(19/139)和 18.71%(26/139)发生了 C6 和 C7 骨折,而年轻患者中这一比例分别为 32.03%(188/587)和 41.40%(243/587)(P < 0.001)。此外,53.96%(75/139)的老年患者因平地跌倒发生了 C 型脊柱骨折,且上颈椎骨折(C1 和 C2)较多。这些患者中只有 3.2%血液酒精水平呈阳性,而年轻患者中这一比例为 52.9%(P < 0.001)。此外,因平地跌倒导致的老年患者中有 6.34%患有颅内病变(ICP),这是 C 型脊柱骨折最常见的并存损伤之一。逻辑回归分析显示,老年平地跌倒患者预测这种 C 型脊柱骨折和 ICP 并存损伤模式的校正比值比分别为 1.17(年龄)和 91.57(男性)。
无论损伤机制如何,老年患者比非老年患者更容易发生上颈椎骨折。平地跌倒或程度更轻的情况不仅可导致孤立的 C 型脊柱骨折,还可导致其他严重损伤,在老年患者中颅内病变是最常见的。高龄和男性是预测这种并存损伤模式的两个危险因素。此外,酒精似乎在老年创伤患者平地跌倒的原因中不起作用。