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本文引用的文献

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Anxiety disorders in children and adolescents with autistic spectrum disorders: a meta-analysis.儿童和青少年自闭症谱系障碍中的焦虑障碍:一项荟萃分析。
Clin Child Fam Psychol Rev. 2011 Sep;14(3):302-17. doi: 10.1007/s10567-011-0097-0.
2
Kiddie-SADS reveals high rates of DSM-IV disorders in children and adolescents with autism spectrum disorders.儿童孤独症谱系障碍患者的 Kiddie-SADS 揭示了 DSM-IV 障碍的高发生率。
J Autism Dev Disord. 2011 Jun;41(6):761-9. doi: 10.1007/s10803-010-1095-7.
3
Psychiatric disorders in individuals with high-functioning autism and Asperger's disorder: similarities and differences.高功能自闭症和阿斯伯格综合征个体的精神障碍:相似与不同。
World J Biol Psychiatry. 2010 Dec;11(8):964-71. doi: 10.3109/15622975.2010.507785. Epub 2010 Aug 24.
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Autistic spectrum disorder traits in children with attention deficit hyperactivity disorder.注意缺陷多动障碍儿童的自闭症谱系障碍特征
Child Care Health Dev. 2011 Jan;37(1):103-10. doi: 10.1111/j.1365-2214.2010.01123.x.
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Inter-rater reliability of the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID I) and Axis II Disorders (SCID II).DSM-IV 轴 I 障碍(SCID I)和轴 II 障碍(SCID II)的结构性临床访谈的评定者间信度。
Clin Psychol Psychother. 2011 Jan-Feb;18(1):75-9. doi: 10.1002/cpp.693.
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Comorbid psychiatric disorders associated with Asperger syndrome/high-functioning autism: a community- and clinic-based study.伴发精神障碍与艾斯伯格综合征/高功能自闭症相关:基于社区和临床的研究。
J Autism Dev Disord. 2010 Sep;40(9):1080-93. doi: 10.1007/s10803-010-0958-2.
7
Psychiatric comorbidity among children and adolescents with and without persistent attention-deficit hyperactivity disorder.伴有和不伴有持续性注意缺陷多动障碍的儿童和青少年的精神共病情况。
Aust N Z J Psychiatry. 2010 Feb;44(2):135-43. doi: 10.3109/00048670903282733.
8
High rates of psychiatric co-morbidity in individuals with Asperger's disorder.阿斯伯格综合征个体的精神共病率较高。
World J Biol Psychiatry. 2010 Mar;11(2 Pt 2):486-92. doi: 10.1080/15622970902789130.
9
Cognitive behavioral therapy for anxiety in children with autism spectrum disorders: a randomized, controlled trial.针对自闭症谱系障碍儿童焦虑症的认知行为疗法:一项随机对照试验。
J Child Psychol Psychiatry. 2009 Mar;50(3):224-34. doi: 10.1111/j.1469-7610.2008.01948.x.
10
Comparative study of children with ADHD only, autism spectrum disorder + ADHD, and chronic multiple tic disorder + ADHD.仅患有注意力缺陷多动障碍(ADHD)的儿童、自闭症谱系障碍合并ADHD的儿童以及慢性多发性抽动障碍合并ADHD的儿童的比较研究。
J Atten Disord. 2009 Mar;12(5):474-85. doi: 10.1177/1087054708320404.

自闭症谱系障碍儿童的精神共病:与注意缺陷多动障碍儿童的比较。

Psychiatric Comorbidity in Children with Autism Spectrum Disorders: A Comparison with Children with ADHD.

作者信息

van Steensel Francisca J A, Bögels Susan M, de Bruin Esther I

机构信息

Research Institute of Child Development and Education, University of Amsterdam, Nieuwe Prinsengracht 130, 1018 VZ Amsterdam, The Netherlands.

出版信息

J Child Fam Stud. 2013 Apr;22(3):368-376. doi: 10.1007/s10826-012-9587-z. Epub 2012 May 1.

DOI:10.1007/s10826-012-9587-z
PMID:23524401
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3602612/
Abstract

The present study was conducted with the aim to identify comorbid psychiatric disorders in children with autism spectrum disorders (ASD) ( = 40) and to compare those comorbidity rates to those in children with attention deficit hyperactivity disorder (ADHD) ( = 40). Participants were clinically referred children aged 7-18 years. DSM-IV classifications were used for the primary diagnosis (ASD/ADHD), while comorbid psychiatric disorders were assessed using a structured diagnostic interview, the structured clinical interview for DSM-IV, childhood diagnoses (KID-SCID). Twenty-three children with ASD (57.5 %) had at least one comorbid disorder, whereas 16 children with ADHD (40.0 %) were classified as having at least one comorbid disorder. No group differences were found with respect to this comorbidity rate or for the rate of comorbid externalizing disorders (ODD and/or CD). However, children with ASD had more comorbid internalizing disorders compared to children with ADHD. More specifically, children with ASD had higher rates of anxiety disorders, but not mood disorders. No associations between comorbidity and age or between comorbidity and the intelligence quotient was found. It is important for clinicians to always be aware of, and screen for, comorbidity, and to consider treatment for these comorbid disorders. In addition, research should focus on establishing valid and reliable screening tools as well as effective treatment options for these comorbid disorders.

摘要

本研究旨在识别自闭症谱系障碍(ASD)儿童(n = 40)中共存的精神障碍,并将这些共病率与注意力缺陷多动障碍(ADHD)儿童(n = 40)的共病率进行比较。参与者为临床转诊的7至18岁儿童。主要诊断(ASD/ADHD)采用《精神疾病诊断与统计手册》第四版(DSM-IV)分类,而共存的精神障碍则使用结构化诊断访谈《DSM-IV儿童诊断用结构化临床访谈》(KID-SCID)进行评估。23名ASD儿童(57.5%)至少有一种共病障碍,而16名ADHD儿童(40.0%)被归类为至少有一种共病障碍。在这种共病率或共病外化障碍(对立违抗障碍和/或品行障碍)率方面未发现组间差异。然而,与ADHD儿童相比,ASD儿童有更多的共病内化障碍。更具体地说,ASD儿童的焦虑障碍发生率较高,但心境障碍发生率并非如此。未发现共病与年龄之间或共病与智商之间存在关联。临床医生始终意识到并筛查共病,并考虑对这些共病障碍进行治疗非常重要。此外,研究应侧重于建立针对这些共病障碍的有效且可靠的筛查工具以及有效的治疗方案。