Chang Shyue-Luen, Huang Yau-Li, Lee Mei-Ching, Chang Chih-Hsiang, Chung Wen-Hung, Wu En-Haw, Hu Sindy
Department of Dermatology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan.
Lasers Med Sci. 2014 Jan;29(1):165-72. doi: 10.1007/s10103-013-1301-x. Epub 2013 Mar 24.
Previous studies have shown that single or multiple treatments by focused ultrasound are effective and safe. However, most include focused ultrasound only and not radio-frequency treatment. There is paucity of magnetic resonance imaging (MRI) measurements and pictures in the literature. This study aimed to assess the efficacy, safety, and pain and satisfaction levels of the combination therapy of focused ultrasound and radio-frequency for improving body contours. Thirty-two Asian patients received 3 sequential treatments every 2 weeks in the abdominal region. Safety parameters and adverse events were recorded. The subjects' pain and satisfaction levels were evaluated using a five-point Likert scale. Two patients underwent MRI study randomly. There was a mean reduction in circumference of 3.91 ± 1.8 cm (p ≤ 0.001). In MRI measurement, the average in fat thickness reduction was 21.4 and 25% on the upper and lower abdomen, respectively. There were three mild and self-limited localized adverse events. The satisfaction survey showed that 71.9% was satisfied with the results, while pain level evaluation showed that 90.5% felt no pain. Combination therapy of focused ultrasound and radio-frequency for noninvasive body contouring is an effective, safe, and painless procedure in Asians. Although the change is minor compared to traditional surgical procedure, it is real, definite, and effective.
以往研究表明，聚焦超声单次或多次治疗是有效且安全的。然而，大多数研究仅包括聚焦超声，而未涉及射频治疗。文献中缺乏磁共振成像（MRI）测量结果和图片。本研究旨在评估聚焦超声与射频联合治疗改善身体轮廓的疗效、安全性、疼痛程度及满意度。32名亚洲患者在腹部区域每2周接受3次连续治疗。记录安全参数和不良事件。使用五点李克特量表评估受试者的疼痛程度和满意度。随机选取两名患者进行MRI检查。平均腰围减少3.91±1.8厘米（p≤0.001）。在MRI测量中，上腹部和下腹部脂肪厚度平均分别减少21.4%和25%。出现3例轻度、自限性局部不良事件。满意度调查显示，71.9%的患者对结果满意，而疼痛程度评估显示，90.5%的患者无疼痛感觉。聚焦超声与射频联合治疗非侵入性身体塑形对亚洲人来说是一种有效、安全且无痛的方法。尽管与传统手术相比变化较小，但却是真实、确切且有效的。
