Basiri Abbas, Soltani Mohammad Hossein, Kamranmanesh Mohammadreza, Tabibi Ali, Mohsen Ziaee Seyed Amir, Nouralizadeh Akbar, Sharifiaghdas Farzaneh, Poorzamani Mahtab, Gharaei Babak, Ozhand Ardalan, Lashay Alireza, Ahanian Ali, Aminsharifi Alireza, Sichani Mehrdad Mohammadi, Asl-Zare Mohammad, Ali Beigi Faramarz Mohammad, Najjaran Vahid, Abedinzadeh Mehdi, Nikkar Mohammad Masoud
Urology and Nephrology Research Center, Shahid Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Korean J Urol. 2013 Mar;54(3):172-6. doi: 10.4111/kju.2013.54.3.172. Epub 2013 Mar 15.
Percutaneous nephrolithotomy (PCNL) has been the preferred procedure for the removal of large renal stones in Iran since 1990. Recently, we encountered a series of devastating neurologic complications during PCNL, including paraplegia and hemiplegia. There are several reports of neurologic complications following PCNL owing to paradoxical air emboli, but there are no reports of paraplegia following PCNL.
We retrospectively reviewed the medical records of patients who had undergone PCNL in 13 different endourologic centers and retrieved data related to neurologic complications after PCNL, including coma, paraplegia, hemiplegia, and quadriplegia.
The total number of PCNL procedures in these 13 centers was 30,666. Among these procedures, 11 cases were complicated by neurologic events, and four of these cases experienced paraplegia. All events happened with the patient in the prone position with the use of general anesthesia and in the presence of air injection. There were no reports of neurologic complications in PCNL procedures performed with the patient under general anesthesia and in the prone position and with contrast injection.
It can be assumed that using room air to opacify the collecting system played a major role in the occurrence of these complications. Likewise, the prone position and general anesthesia may predispose to these events in the presence of air injection.
自1990年以来,经皮肾镜取石术(PCNL)一直是伊朗治疗大型肾结石的首选方法。最近,我们在PCNL过程中遇到了一系列严重的神经系统并发症,包括截瘫和偏瘫。有几篇关于PCNL后因反常空气栓塞导致神经系统并发症的报道,但尚无PCNL后发生截瘫的报道。
我们回顾性分析了13个不同腔内泌尿外科中心接受PCNL治疗的患者的病历,并收集了与PCNL后神经系统并发症相关的数据,包括昏迷、截瘫、偏瘫和四肢瘫。
这13个中心的PCNL手术总数为30666例。在这些手术中,11例出现神经系统事件,其中4例发生截瘫。所有事件均发生在患者处于俯卧位、使用全身麻醉且有空气注入的情况下。在全身麻醉下患者处于俯卧位并注入造影剂的PCNL手术中,未报告有神经系统并发症。
可以推测,使用室内空气使集合系统显影在这些并发症的发生中起了主要作用。同样,俯卧位和全身麻醉在有空气注入的情况下可能易引发这些事件。