Boyraz Gokhan, Selcuk Ilker, Yusifli Zarife, Usubutun Alp, Gunalp Serdar
Department of Obstetrics and Gynecology, Hacettepe University Faculty of Medicine, 06100 Ankara, Turkey.
Case Rep Med. 2013;2013:527698. doi: 10.1155/2013/527698. Epub 2013 Feb 21.
Steroid cell tumors (SCTs) of the ovary are a rare subgroup of sex cord tumors, account for less than 0.1% of all ovarian tumors, and also will present at any age. These tumors can produce steroids, especially testosterone, and may give symptoms like hirsutism, hair loss, amenorrhea, or oligomenorrhea. For the evaluation of androgen excess, testosterone and dehydroepiandrosterone sulfate (DHEA-S) are the first laboratory tests to be measured. A pelvic ultrasound and a magnetic resonance imaging are useful radiologic imaging techniques. Although steroid cell tumors are generally benign, there is a risk of malignant transformation and clinical malignant formation. Surgery is the most important and hallmark treatment.
卵巢类固醇细胞瘤(SCTs)是性索肿瘤中的一个罕见亚组,占所有卵巢肿瘤的比例不到0.1%,且可在任何年龄出现。这些肿瘤可产生类固醇,尤其是睾酮,并可能出现多毛、脱发、闭经或少经等症状。对于雄激素过多的评估,睾酮和硫酸脱氢表雄酮(DHEA-S)是首先要检测的实验室指标。盆腔超声和磁共振成像都是有用的放射学成像技术。虽然类固醇细胞瘤一般为良性,但存在恶性转化和临床恶性形成的风险。手术是最重要的标志性治疗方法。