Kosaraju Kranthi, Faujdar Sameer Singh, Singh Aashima, Prabhu Ravindra
Department of Microbiology, Kasturba Medical College and Hospital, Manipal University, Madhav Nagar, Manipal 576104, Karnataka, India.
Hepat Res Treat. 2013;2013:860514. doi: 10.1155/2013/860514. Epub 2013 Mar 6.
Hepatitis B (HBV) and hepatitis C (HCV) viruses are the most important causes of chronic liver disease in patients with end stage renal disease on hemodialysis. The prevalence of hepatitis infection among hemodialysis patients is high and varies between countries and between dialysis units within a single country. This case-control study was undertaken to estimate the occurrence of HBV and HCV infections in patients undergoing hemodialysis in our tertiary care center. All patients receving hemodialysis at our centre with HCV or HBV infection were included in the study. The total number of patients admitted for hemodialysis during the study period was 1710. Among these, 26 patients were positive for HBV, 19 were positive for HCV, and 2 were positive for both HCV and HBV. Mean age of the infected cases in our study was 48.63 years. Mean duration of dialysis for infected cases was 4.8 years while that of the noninfected controls was 3.18 years. The mean dialysis interval was twice a week. Interventions to reduce the occurrence of these infections are of utmost need to reduce the risk of long-term complications among hemodialysis patients.
乙型肝炎病毒（HBV）和丙型肝炎病毒（HCV）是接受血液透析的终末期肾病患者慢性肝病的最重要病因。血液透析患者中肝炎感染的患病率很高，且在不同国家以及同一国家内的不同透析单位之间存在差异。本病例对照研究旨在评估在我们的三级医疗中心接受血液透析的患者中HBV和HCV感染的发生率。在我们中心接受血液透析且感染HCV或HBV的所有患者均纳入研究。研究期间接受血液透析的患者总数为1710例。其中，26例HBV呈阳性，19例HCV呈阳性，2例HCV和HBV均呈阳性。我们研究中感染病例的平均年龄为48.63岁。感染病例的平均透析时长为4.8年，而未感染对照组的平均透析时长为3.18年。平均透析间隔为每周两次。迫切需要采取干预措施以减少这些感染的发生，从而降低血液透析患者发生长期并发症的风险。
