Leng Jennifer, Peruluswami Ponni, Bari Sehrish, Gaur Sunanda, Radparvar Farshid, Parvez Faruque, Chen Yu, Flores Cristina, Gany Francesca
Department of Psychiatry and Behavioral Sciences, Immigrant Health and Cancer Disparities Service, Memorial Sloan Kettering Cancer Center, 485 Lexington Avenue, 2nd Floor, New York, NY, 10017, USA.
Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, USA.
J Immigr Minor Health. 2019 Aug;21(Suppl 1):26-36. doi: 10.1007/s10903-017-0652-y.
This paper presents the results of the literature review conducted for the working group topic on inflammation, infection, exposure, and the human microbiome. Infection and chronic inflammation can elevate risk for cardiovascular disease and cancer. Environmental exposures common among South Asian (SA) subgroups, such as arsenic exposure among Bangladeshis and particulate matter air pollution among taxi drivers, also pose risks. This review explores the effects of exposure to arsenic and particulate matter, as well as other infections common among SAs, including human papillomavirus (HPV) and hepatitis B/C infection. Emerging research on the human microbiome, and the effect of microbiome changes on obesity and diabetes risk among SAs are also explored.
本文介绍了针对炎症、感染、暴露及人类微生物组这一工作组主题所进行的文献综述结果。感染和慢性炎症会增加心血管疾病和癌症的风险。南亚（SA）亚组中常见的环境暴露，如孟加拉人接触砷以及出租车司机接触颗粒物空气污染，也会带来风险。本综述探讨了接触砷和颗粒物的影响，以及南亚人中常见的其他感染，包括人乳头瘤病毒（HPV）和乙型/丙型肝炎感染。还探讨了关于人类微生物组的新兴研究，以及微生物组变化对南亚人肥胖和糖尿病风险的影响。
