Daniel G A, Entin M A, Kahn D S
Can J Surg. 1975 Jan;18(1):53-60.
Thirty free autogenous metacarpal and 26 phalangeal articular cartilages were transplanted in the forefoot of dogs. The graft in each case included the articular surface and a minimal amount of supporting subchondral bone. The majority of the metacarpal grafts retained a normal gross, microscopic, and radioautographic appearance, some for up to 1 year after transplantation. In contradistinction, all of the phalangeal grafts failed, probably because their flatt surface made it impossible to maintain adequate fixation to the host bed. As a result the majority of these grafts became displaced. Analysis of the incorporation of the metacarpal grafts into the host bed showed that this occurred when there was no significant period during which the articular cartilage was without subchondral support. The situation is different in the case of joint grafts with a larger amount of subchondral bone. In these, during the time that this necrotic bone is being resorbed and replaced by normal viable bone, the articular cartilage has extremely limited subchondral support.
将30块游离自体掌骨和26块指骨关节软骨移植到犬的前足。每例移植物均包括关节面和少量支持性软骨下骨。大多数掌骨移植物在移植后长达1年的时间里保持正常的大体、显微镜及放射自显影表现。相反，所有指骨移植物均失败，可能是因为其扁平表面使得无法与宿主床保持充分固定。结果，这些移植物大多发生移位。对掌骨移植物与宿主床结合情况的分析表明，当关节软骨在无软骨下支持的情况下不存在明显时间段时，就会发生这种结合。对于含有较多软骨下骨的关节移植物，情况则不同。在这些移植物中，在坏死骨被正常活骨吸收并替代的过程中，关节软骨的软骨下支持极其有限。
