Pamukkale University Medicine Faculty Psychiatry Department, Doktorlar Cd, 20100 Denizli, Turkey.
Psychiatry Res. 2013 Oct 30;209(3):579-88. doi: 10.1016/j.psychres.2013.02.009. Epub 2013 Mar 26.
Past studies have suggested that OCD patients suffer memory impairment on tasks using complex stimuli that require memory for combined elements to be maintained, but not for more simplistic memory tests. We tested this with 42 OCD patients and 42 healthy controls performed a computerized situation awareness task. In addition, participants completed the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) and Maudsley Obsessive-Compulsive Inventory (MOCI). The OCD patients had poorer accuracy in integration/comprehension and perception levels than controls. There were significant correlations between situational awareness scores (i.e., visuo-spatial monitoring and processing) and Y-BOCS obsession-compulsion and slowness and doubt scores of MOCI in OCD patients. In addition, there were also significant correlations between situational awareness and controlling, cleaning, slowness, rumination and total scores of MOCI in control group. Results indicated that (I) OCD patients have problems of perception, integration, and comprehension of complex visual perceptions; (II) situation awareness deficits associated with severity and prevalence of obsessions and compulsions.
过去的研究表明,强迫症患者在使用需要记忆组合元素的复杂刺激的任务中会出现记忆损伤,但在更简单的记忆测试中不会。我们用 42 名强迫症患者和 42 名健康对照者进行了一项计算机情景意识任务来检验这一点。此外,参与者还完成了耶鲁-布朗强迫症量表(Y-BOCS)和莫兹利强迫症量表(MOCI)。强迫症患者在整合/理解和感知水平上的准确性比对照组差。在强迫症患者中,情景意识评分(即视空间监测和处理)与 Y-BOCS 的强迫观念-强迫行为以及 MOCI 的缓慢和疑虑评分之间存在显著相关性。此外,在对照组中,情景意识与控制、清洁、缓慢、沉思和 MOCI 的总分之间也存在显著相关性。结果表明:(I)强迫症患者在复杂视觉感知的感知、整合和理解方面存在问题;(II)情景意识缺陷与强迫观念和强迫行为的严重程度和普遍性有关。