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双支架辅助弹簧圈栓塞治疗分叉部动脉瘤:即刻治疗结果和长期血管造影结果。

Double stent-assisted coil embolization treatment for bifurcation aneurysms: immediate treatment results and long-term angiographic outcome.

机构信息

From Hacettepe University Hospitals, Interventional Neuroradiology Department, Ankara, Turkey.

出版信息

AJNR Am J Neuroradiol. 2013 Sep;34(9):1778-84. doi: 10.3174/ajnr.A3464. Epub 2013 Mar 28.

Abstract

BACKGROUND AND PURPOSE

The goal of endovascular treatment of cerebral bifurcation aneurysms is to achieve safe coiling of the sac along with preserving patency of the diverging branches. Our purpose was evaluate procedural safety and efficacy as well as the long-term durability of endovascular treatment of bifurcation aneurysms with double stent-assisted coiling.

MATERIALS AND METHODS

One hundred ninety-one consecutive patients with bifurcation aneurysms were included in this series. Technical failure occurred in 3 aneurysms (1.5%); 188 patients with 193 aneurysms treated with double stent-assisted coiling were retrospectively evaluated; 113 aneurysms were located at middle cerebral artery bifurcation, 42 at the anterior communicating artery, 22 at the basilar artery bifurcation, and the remaining 16 at the internal carotid artery bifurcation; 132 were small (<10 mm), 56 were large (10-25 mm), and 5 were giant (>25 mm).

RESULTS

The technical success rate of double-stent application was 98.5% (193 aneurysms). In total, there were 5 procedural complications with an associated rate of 2.7%, one of which led to death (0.5%). Delayed ischemic stroke occurred in 2 patients (1.1%). Overall, permanent morbidity occurred in 2 patients, with associated rate of 1.1%. Follow-up was obtained in 186 aneurysms (96.4%), and recanalization occurred in 4 aneurysms (2.2%). In subgroup analysis, the recanalization rate was 3.8% for large aneurysms and 40% for giant aneurysms. No recanalization occurred in small aneurysms.

CONCLUSIONS

Dual stent-assisted coiling of cerebral aneurysms is a feasible and safe procedure. It may offer a curative solution with long-term durability for treatment of wide-neck small and large aneurysms.

摘要

背景与目的

血管内治疗脑分叉部动脉瘤的目的是安全地填塞瘤囊并保持分叉部分支的通畅。本研究旨在评估双支架辅助弹簧圈栓塞术治疗分叉部动脉瘤的安全性和有效性,以及长期疗效。

材料与方法

本研究纳入了 191 例连续的分叉部动脉瘤患者。3 例(1.5%)出现技术失败,188 例患者的 193 个分叉部动脉瘤接受了双支架辅助弹簧圈栓塞术治疗,回顾性分析了这些患者的资料;其中 113 个动脉瘤位于大脑中动脉分叉部,42 个位于前交通动脉,22 个位于基底动脉分叉部,16 个位于颈内动脉分叉部;132 个动脉瘤直径<10mm,56 个直径为 10-25mm,5 个直径>25mm。

结果

双支架应用的技术成功率为 98.5%(193 个动脉瘤)。共有 5 例出现操作相关并发症,发生率为 2.7%,其中 1 例导致患者死亡(0.5%)。2 例患者出现迟发性缺血性卒中(1.1%)。总的来说,2 例患者发生永久性并发症,发生率为 1.1%。186 个动脉瘤获得了随访(96.4%),4 个动脉瘤出现再通(2.2%)。亚组分析显示,大型和巨大型动脉瘤的再通率分别为 3.8%和 40%,小型动脉瘤无再通发生。

结论

双支架辅助弹簧圈栓塞术治疗脑动脉瘤是一种可行且安全的方法,对于治疗宽颈小、大型动脉瘤,它可能是一种具有长期疗效的治疗选择。

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