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计算机辅助精液分析与体外受精程序中卵母细胞成功受精的相关性。

Correlation of computerized semen analysis with successful fertilization of oocytes in an in vitro fertilization program.

作者信息

Check J H, Bollendorf A, Lee M A, Nazari A, Nowroozi K

机构信息

Department of Obstetrics and Gynecology, Cooper Hospital/University Medical Center, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Camden.

出版信息

Arch Androl. 1990;24(3):229-34. doi: 10.3109/01485019008987579.

DOI:10.3109/01485019008987579
PMID:2353846
Abstract

Sixty-nine couples enrolled in 123 in vitro fertilization-embryo transfer cycles were categorized by percentage fertilization; the results of categorization were compared with those of computerized semen analysis carried out with the CellSoft semen analyzer. Four groups were established: group 1 had 75% fertilization or greater; group 2 had 34% to 74% fertilization; group 3 had 1% to 33% fertilization; and group 4 had 0% fertilization. Statistical differences in certain semen parameters (motility, linearity, and straight-line velocity) were found comparing groups 1 and 3 using the initial ejaculate. A significant number of patients in group 1 had all normal semen parameters, but no statistical difference could be found in group 3 or 4 because of variations in specific abnormal parameters in the groups. When the straight-line velocity-motile density (SLVMD) calculation was used, a significant difference was seen between group 1 and group 3 and between group 1 and group 4 (p less than 0.01); 65% of group 3 and 76% of group 4 had an abnormal SLVMD. SLVMD is a useful calculation to predict fertilization rates in vitro from the initial ejaculate.

摘要

69对参与123个体外受精 - 胚胎移植周期的夫妇按受精率进行分类;分类结果与使用CellSoft精液分析仪进行的计算机化精液分析结果进行比较。共分为四组:第1组受精率为75%或更高;第2组受精率为34%至74%;第3组受精率为1%至33%;第4组受精率为0%。使用初始射精样本比较第1组和第3组时,发现某些精液参数(活力、直线性和直线速度)存在统计学差异。第1组中有相当数量的患者精液参数全部正常,但由于第3组和第4组中特定异常参数的变化,未发现统计学差异。当使用直线速度 - 活动密度(SLVMD)计算时,第1组和第3组之间以及第1组和第4组之间存在显著差异(p小于0.01);第3组的65%和第4组的76%的SLVMD异常。SLVMD是一种从初始射精样本预测体外受精率的有用计算方法。

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Correlation of computerized semen analysis with successful fertilization of oocytes in an in vitro fertilization program.计算机辅助精液分析与体外受精程序中卵母细胞成功受精的相关性。
Arch Androl. 1990;24(3):229-34. doi: 10.3109/01485019008987579.
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J Androl. 1991 Jul-Aug;12(4):231-9.
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Conventional in vitro fertilization versus intracytoplasmic sperm injection in patients with borderline semen: a randomized study using sibling oocytes.精液质量临界患者常规体外受精与卵胞浆内单精子注射的比较:一项使用姐妹卵母细胞的随机研究。
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Does computerized image analysis of sperm movement enhance the predictive value of semen analysis for in-vitro fertilization results?精子运动的计算机图像分析能否提高精液分析对体外受精结果的预测价值?
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Examination of data from programs of in vitro fertilization in relation to sperm integrity and reproductive success.关于精子完整性与生殖成功率的体外受精程序数据研究。
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Comparison of sperm parameters, in vitro fertilization results, and subsequent pregnancy rates using sequential ejaculates, collected two hours apart, from oligoasthenozoospermic men.对少弱精子症男性每隔两小时采集的连续射精样本的精子参数、体外受精结果及后续妊娠率进行比较。
Fertil Steril. 1995 Nov;64(5):1008-11. doi: 10.1016/s0015-0282(16)57920-5.

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