在麻疹疫情期间区分野生毒株和减毒毒株。
Differentiating the wild from the attenuated during a measles outbreak.
作者信息
Nestibo Lindsay, Lee Bonita E, Fonseca Kevin, Beirnes Jennifer, Johnson Marcia M, Sikora Christopher A
机构信息
Communicable Disease Control, Alberta Health Services;
出版信息
Paediatr Child Health. 2012 Apr;17(4):e32-3. doi: 10.1093/pch/17.4.e32.
Abstract
In the midst of a local measles outbreak, a recently immunized child was investigated for a new-onset measles-type rash. Nucleic acid testing identified that a vaccine-type measles virus was being shed in the urine. Clinically differentiating measles from a nonmeasles rash is challenging, but can be supported by a thorough medical history evaluation. Rashes are expected to occur after immunization; nucleic acid testing can be used when it is difficult to differentiate between wild and attenuated strains.
摘要
在当地麻疹疫情爆发期间，对一名近期接种过疫苗的儿童进行了调查，该儿童出现了新发的麻疹样皮疹。核酸检测发现尿液中排出的是疫苗株麻疹病毒。临床上区分麻疹和非麻疹皮疹具有挑战性，但全面的病史评估有助于诊断。接种疫苗后可能会出现皮疹；当难以区分野生株和减毒株时，可进行核酸检测。
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