用于医学成像应用的多镧系元素体系。
Multilanthanide Systems for Medical Imaging Applications.
作者信息
Moore Jeremiah D, Allen Matthew J
出版信息
Recent Pat Nanomed. 2011 Dec 1;1(2):88-100. doi: 10.2174/1877912311101020088.
Abstract
Molecules containing multiple lanthanide ions have unique potential in applications for medical imaging including the areas of magnetic resonance imaging (MRI) and fluoresence imaging. The study of multilanthanide complexes as contrast agents for MRI and as biologically responsive fluorescent probes has resulted in an improved understanding of the structural characteristics that govern the behavior of these complexes. This review will survey the last five years of progress in multinuclear lanthanide complexes with a specific focus on the structural parameters that impact potential medical imaging applications. The patents cited in this review are from the last five years and describe contrast agents that contain multiple lanthanide ions.
摘要
含有多个镧系离子的分子在包括磁共振成像（MRI）和荧光成像等医学成像应用中具有独特的潜力。对多镧系配合物作为MRI造影剂和生物响应荧光探针的研究，增进了我们对控制这些配合物行为的结构特征的理解。本综述将概述多核镧系配合物在过去五年中的进展，特别关注影响潜在医学成像应用的结构参数。本综述中引用的专利来自过去五年，描述了含有多个镧系离子的造影剂。
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