糖尿病与心血管疾病：弗雷明汉心脏研究的独到见解
Diabetes and Cardiovascular Disease: Original Insights from the Framingham Heart Study.
作者信息
Qazi Mohammad U, Malik Shaista
机构信息
Department of Medicine, University of California, Irvine.
出版信息
Glob Heart. 2013 Mar 1;8(1):43-48. doi: 10.1016/j.gheart.2012.12.008.
Abstract
The role of diabetes in the pathogenesis of cardiovascular disease (CVD) was unclear until 1979 when Kannel et al used data from the Framingham Heart Study (FHS) to identify diabetes as a major cardiovascular risk factor. It was also one of the first studies to demonstrate the higher risk of CVD in women with diabetes compared to men with diabetes. Since then, multiple studies have been done to recognize and curtail cardiovascular risk factors such as smoking, obesity, hypertension, hyperlipidemia, and insulin resistance. This review will examine the contribution of the Kannel article and subsequent studies in defining the contribution of several risk factors on cardiovascular disease.
摘要
直到1979年，卡内尔等人利用弗雷明汉心脏研究（FHS）的数据将糖尿病确定为主要心血管危险因素，糖尿病在心血管疾病（CVD）发病机制中的作用才得以明确。这也是最早表明糖尿病女性患心血管疾病风险高于糖尿病男性的研究之一。从那时起，人们开展了多项研究来识别和减少心血管危险因素，如吸烟、肥胖、高血压、高脂血症和胰岛素抵抗。本综述将探讨卡内尔的文章及后续研究在确定多种危险因素对心血管疾病的影响方面所做的贡献。
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