Gaxiola-Robles Ramón, Celis Alfredo, Serrano-Pinto Vania, Orozco-Valerio María de Jesús, Zenteno-Savín Tania
Centro de Investigaciones Biológicas del Noroeste (CIBNOR), Planeaci6n Ambiental y Conservación, La Paz, Baja California Sur.
Rev Invest Clin. 2012 Sep-Oct;64(5):444-51.
To describe the mortality of dengue in Mexico during 1980 to 2009.
Dengue mortality data for Mexico were obtained from Instituto Nacional de Estadistica, Geografía e Informática. We used standardized and non-standardized dengue mortality rates per 1,000,000 people and determined the mortality trend. The groups were based on International Classification of Diseases coding criteria (ICD-9 E061 and ICD-10 A91X). The results were stratified by age groups and the frequencies of dengue deaths were compared using relative risk (RR) with its 95% confidence interval.
During 1980 to 2009 in Mexico, 549 deaths due to dengue were reported. We found an important variation in the mortality rates during the years studied. We were able to identify three periods: 1980 to 1992, 1994 to 2000, and 2001 to 2009. The mortality rates found are from 0.88/1,000,000 through 0.00/1,000,000. The average mortality rates by decade: 1980 to 1989: 0.53/1,000,000; 1990 to 1999: 0.06/1,000,000; 2000 to 2009: 0.12/1,000,000. In the analysis of mortality by community size during 2000 to 2009, we observed in the small communities with < 2,499 people, the risk is 1.25 times higher than in those with more than 20,000 people.
We found, in general, a sustained decline in the number of deaths by dengue over the last 30 years in Mexico. However, a slow increase was observed since 1994, which may be related to the circulation of DENV2 and DENV3, among other factors. We need to strengthen prevention programs in smaller communities (< 2,499) where we found a higher risk of mortality due to dengue.
描述1980年至2009年期间墨西哥登革热的死亡率。
墨西哥登革热死亡率数据取自国家统计、地理与信息研究所。我们使用了每百万人的标准化和非标准化登革热死亡率，并确定了死亡率趋势。分组基于国际疾病分类编码标准（ICD - 9 E061和ICD - 10 A91X）。结果按年龄组进行分层，并使用相对风险（RR）及其95%置信区间比较登革热死亡频率。
1980年至2009年期间，墨西哥报告了549例登革热死亡病例。我们发现在所研究的年份中死亡率存在重要差异。我们能够确定三个时期：1980年至1992年、1994年至2000年以及2001年至2009年。所发现的死亡率从0.88/百万至0.00/百万不等。按十年计算的平均死亡率：1980年至1989年：0.53/百万；1990年至1999年：0.06/百万；2000年至2009年：0.12/百万。在对2000年至2009年期间按社区规模进行的死亡率分析中，我们观察到，在人口少于2499人的小社区中，风险比人口超过20000人的社区高1.25倍。
总体而言，我们发现过去30年墨西哥登革热死亡人数持续下降。然而，自1994年以来观察到缓慢上升，这可能与登革热病毒2型和登革热病毒3型的传播以及其他因素有关。我们需要加强在较小社区（人口少于2499人）的预防项目，在这些社区我们发现登革热导致死亡的风险更高。
