Department of Neurosurgery, Section of Neuroradiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Neurosurg Focus. 2013 Apr;34(4):E1. doi: 10.3171/2013.1.FOCUS12412.
Diffusion tensor imaging (DTI) is increasingly used in the resection of both high- and low-grade gliomas. Whereas conventional MRI techniques provide only anatomical information, DTI offers data on CNS connectivity by enabling visualization of important white matter tracts in the brain. Importantly, DTI allows neurosurgeons to better guide their surgical approach and resection. Here, the authors review basic scientific principles of DTI, include a primer on the technology and image acquisition, and outline the modality's evolution as a frequently used tool for glioma resection. Current literature supporting its use is summarized, highlighting important clinical studies on the application of DTI in preoperative planning for glioma resection, preoperative diagnosis, and postoperative outcomes. The authors conclude with a review of future directions for this technology.
弥散张量成像（DTI）越来越多地用于高级和低级胶质瘤的切除。传统的 MRI 技术仅提供解剖学信息，而 DTI 通过可视化大脑中的重要白质束，提供有关中枢神经系统连接的数据。重要的是，DTI 使神经外科医生能够更好地指导他们的手术方法和切除。在这里，作者回顾了 DTI 的基本科学原理，包括技术和图像采集的入门知识，并概述了该技术作为胶质瘤切除的常用工具的演变。总结了支持其使用的当前文献，重点介绍了 DTI 在胶质瘤切除术前规划、术前诊断和术后结果中的应用的重要临床研究。作者最后回顾了该技术的未来发展方向。
