Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard. New Delhi -110062, India.
Mini Rev Med Chem. 2013 May 1;13(6):921-31. doi: 10.2174/1389557511313060012.
Pyrazoline is an important five membered nitrogen heterocycle, which has been extensively researched upon. The ring is quite stable and has inspired chemists to carry out various structural variations in the ring. This has propelled the development of distinct pyrazolines with an array of pharmacological activities viz. anti-inflammatory, analgesic, antimicrobial, anticancer, antidepressant etc. The review aims at highlighting this pharmacological diversity of pyrazolines. The review is a gist of latest work done describing the pharmacological aspects and potential of pyrazoline ring.
吡唑啉是一种重要的五元含氮杂环，已经得到了广泛的研究。该环非常稳定，激发了化学家对环进行各种结构变化。这推动了具有多种药理活性的独特吡唑啉的发展，如抗炎、镇痛、抗菌、抗癌、抗抑郁等。本文旨在强调吡唑啉的这种药理学多样性。本文综述了最新的工作，描述了吡唑啉环的药理学方面和潜力。
