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新型Meridol口臭牙齿与舌部凝胶联合舌刷减少口腔异味的短期临床疗效

Short term clinical efficacy of new meridol HALITOSIS tooth & tongue gel in combination with a tongue cleaner to reduce oral malodor.

作者信息

Wilhelm D, Himmelmann A, Krause C, Wilhelm K-P

机构信息

proDERM Institute for Applied Dermatological Research GmbH, Schenefeld, Germany.

出版信息

J Clin Dent. 2013;24(1):12-9.

PMID:23547489
Abstract

OBJECTIVE

This study evaluated the short term efficacy of tongue cleaning with meridol HALITOSIS tooth & tongue gel in comparison to mechanical tongue cleaning alone and untreated after five and 60 minutes in patients with an oral cause of bad breath.

METHODS

Fifty-four male and female subjects with an intra-oral cause of halitosis (organoleptic ratings > or = 2 and volatile sulphur compounds > or = 50 ppb) participated in this crossover study and were assigned to six different treatment sequences (ABC, ACB, BAC, BCA, CAB, CBA) with no treatment (A), mechanical tongue cleaning alone (B), and tongue cleaning with tooth & tongue gel applied to the tongue cleaner (C). Efficacy was assessed by organoleptic ratings and volatile sulphur compound measurements five and 60 minutes after treatment

RESULTS

Cleaning the tongue with tooth & tongue gel applied onto the tongue cleaner resulted in significantly reduced organoleptic ratings (p < 0.001 for the five-minute assessment; p = 0.001 for the 60-minute assessment) and volatile sulphur compounds (H2S + CH3SH: p = 0.005 for the five-minute assessment; p = 0.003 for the 60-minute assessment) compared to no treatment at the five- and 60-minute assessment time points, while mechanical tongue cleaning alone was less effective in reducing organoleptic ratings (p = 0.008 for the five-minute assessment; p = 0.144 for the 60-minute assessment) and volatile sulphur compounds (H2S + CH3SH: p = 0.261 for the five-minute assessment; p = 0.365 for the 60-minute assessment).

CONCLUSIONS

Single tongue cleaning with meridol HALITOSIS tooth & tongue gel had a positive effect on halitosis five and 60 minutes after treatment. Tongue cleaning with tooth & tongue gel in combination with other oral hygiene procedures is a promising approach to control halitosis.

摘要

目的

本研究评估了使用含漱立爽口清新护龈洁舌啫喱清洁舌头的短期疗效,并将其与仅进行机械性舌面清洁及未治疗的情况相比较,观察口腔源性口臭患者在5分钟和60分钟后的效果。

方法

54名患有口腔源性口臭的男女受试者(感官评分≥2且挥发性硫化物≥50 ppb)参与了这项交叉研究,并被分配到六种不同的治疗顺序(ABC、ACB、BAC、BCA、CAB、CBA),分别为不治疗(A)、仅进行机械性舌面清洁(B)以及使用涂抹在舌刷上的护龈洁舌啫喱清洁舌头(C)。在治疗后5分钟和60分钟,通过感官评分和挥发性硫化物测量来评估疗效。

结果

与在5分钟和60分钟评估时间点未治疗相比,使用涂抹在舌刷上的护龈洁舌啫喱清洁舌头可显著降低感官评分(5分钟评估时p<0.001;60分钟评估时p = 0.001)和挥发性硫化物(H2S + CH3SH:5分钟评估时p = 0.005;60分钟评估时p = 0.003),而仅进行机械性舌面清洁在降低感官评分(5分钟评估时p = 0.008;60分钟评估时p = 0.144)和挥发性硫化物(H2S + CH3SH:5分钟评估时p = 0.261;60分钟评估时p = 0.365)方面效果较差。

结论

单次使用含漱立爽口清新护龈洁舌啫喱清洁舌头在治疗后5分钟和60分钟对口臭有积极效果。将护龈洁舌啫喱清洁舌头与其他口腔卫生措施相结合是控制口臭的一种有前景的方法。

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