Komleh K, Hada P, Pendse A K, Singh P P
Department of Biochemistry, R.N.T. Medical College, Udaipur, India.
Int Urol Nephrol. 1990;22(2):113-8. doi: 10.1007/BF02549826.
Serum zinc, copper and manganese levels were estimated in normal subjects (NS) and stone formers (SF). There was no significant difference in the serum levels of Zn, Cu, and Mn in NS and SF, the values being 101.5 +/- 35.1 micrograms% and 94.3 +/- 45.6 for Zn; 91.75 +/- 27.0 micrograms% and 88.5 +/- 34.1 for Cu; and 87.0 +/- 36.7 micrograms% and 79.6 +/- 35.5 for Mn, respectively. Zinc excretion was relatively high in NS (790.08 +/- 172.88 micrograms/dl) as compared to other populations and was significantly higher in SF (1154.92 +/- 290.17 micrograms%, p less than 0.001). Copper and manganese excretions in SF were significantly lower than in NS (p less than 0.001). Zinc was present in substantial quantities in renal (2.52 +/- 3.98 g%), ureteric (0.75 +/- 0.51 g%) and vesical (1.71 +/- 3.20 g%) stones. Manganese was present in traces in all the stones and copper in two-thirds of the stones.
对正常受试者（NS）和结石形成者（SF）的血清锌、铜和锰水平进行了评估。NS和SF的血清锌、铜和锰水平无显著差异，锌的水平分别为101.5±35.1微克%和94.3±45.6；铜为91.75±27.0微克%和88.5±34.1；锰为87.0±36.7微克%和79.6±35.5。与其他人群相比，NS的锌排泄量相对较高（790.08±172.88微克/分升），且SF的锌排泄量显著更高（1154.92±290.17微克%，p<0.001）。SF的铜和锰排泄量显著低于NS（p<0.001）。锌大量存在于肾（2.52±3.98克%）、输尿管（0.75±0.51克%）和膀胱（1.71±3.20克%）结石中。锰在所有结石中微量存在，铜在三分之二的结石中存在。
