Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, PR China.
Eur Neurol. 2013;69(6):331-5. doi: 10.1159/000346813. Epub 2013 Mar 14.
BACKGROUND/AIMS: The aim of this study is to highlight the variable clincoradiological spectrum of isolated cortical vein thrombosis (ICoVT), which seems to remain a challenge to clinicians.
We reported 3 patients with this diagnosis. One presented with only an epileptic seizure, one with worsening headache, seizures, mental disorder, speech disturbance and right-sided weakness, and the other with seizures and fluctuating paralysis in her left-sided limbs. Brain images were manifested with a strand-like abnormal signal, a large hemorrhagic infarction and a continuously enlarged space-occupying massive edema, respectively.
Neurologic features and brain imaging of ICoVT are highly variable, which might be partly responsible for the underestimation of ICoVT. Clinical diagnosis should probably be evoked more often.
背景/目的：本研究旨在强调孤立性大脑皮质静脉血栓形成（ICoVT）的多变临床-放射学特征，这似乎对临床医生仍是一个挑战。
我们报告了 3 例该诊断的患者。1 例仅表现为癫痫发作，1 例表现为头痛加重、癫痫、精神障碍、言语障碍和右侧无力，另 1 例表现为癫痫和左侧肢体间歇性瘫痪。脑部图像分别表现为线状异常信号、大的出血性梗死和不断扩大的占位性大面积水肿。
ICoVT 的神经特征和脑部影像学表现高度多变，这可能部分导致了 ICoVT 的低估。可能需要更经常地提出临床诊断。
