超保护性潮气量：我们应降至多低？
Ultra-protective tidal volume: how low should we go?
作者信息
Costa Eduardo L V, Amato Marcelo B P
出版信息
Crit Care. 2013 Mar 28;17(2):127. doi: 10.1186/cc12556.
Abstract
Applying tidal volumes of less than 6 mL/kg might improve lung protection in patients with acute respiratory distress syndrome. In a recent article, Retamal and colleagues showed that such a reduction is feasible with conventional mechanical ventilation and leads to less tidal recruitment and overdistension without causing carbon dioxide retention or auto-positive end-expiratory pressure. However, whether the compensatory increase in the respiratory rate blunts the lung protection remains unestablished.
摘要
应用小于6 mL/kg的潮气量可能会改善急性呼吸窘迫综合征患者的肺保护。在最近的一篇文章中，雷塔马尔及其同事表明，采用传统机械通气减少潮气量是可行的，并且可减少潮气量导致的肺复张和过度扩张，同时不会引起二氧化碳潴留或内源性呼气末正压。然而，呼吸频率的代偿性增加是否会削弱肺保护作用仍未明确。
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