College of Health & Rehabilitation Sciences: Sargent, Center for Neurorehabilitation, Boston University, MA 02215, USA.
Am J Phys Med Rehabil. 2013 Jun;92(6):472-81; quiz 482-5. doi: 10.1097/PHM.0b013e31828cd466.
The short-term benefits of exercise for persons with Parkinson disease (PD) are well established, but long-term adherence is limited. The aim of this study was to explore the feasibility, acceptability, and preliminary evidence of the effectiveness of a virtual exercise coach to promote daily walking in community-dwelling persons with Parkinson disease.
Twenty subjects with Parkinson disease participated in this phase 1, single-group, nonrandomized clinical trial. The subjects were instructed to interact with the virtual exercise coach for 5 mins, wear a pedometer, and walk daily for 1 mo. Retention rate, satisfaction, and interaction history were assessed at 1 mo. Six-minute walk and gait speed were assessed at baseline and after the intervention.
Fifty-five percent of the participants were women, and the mean age was 65.6 yrs. At the study completion, there was 100% retention rate. The subjects had a mean satisfaction score of 5.6/7 (with 7 indicating maximal satisfaction) with the virtual exercise coach. Interaction history revealed that the participants logged in for a mean (SD) of 25.4 (7) days of the recommended 30 days. The mean adherence to daily walking was 85%. Both gait speed and the 6-min walk test significantly improved (P < 0.05). No adverse events were reported.
Sedentary persons with Parkinson disease successfully used a computer and interacted with a virtual exercise coach. Retention, satisfaction, and adherence to daily walking were high for 1 mo, and significant improvements were seen in mobility.
运动对帕金森病（PD）患者的短期益处已得到充分证实，但长期坚持运动的情况有限。本研究旨在探索虚拟运动教练促进社区居住的帕金森病患者日常步行的可行性、可接受性和初步有效性证据。
20 名帕金森病患者参加了这项 1 期、单组、非随机临床试验。指导患者与虚拟运动教练互动 5 分钟，佩戴计步器，每天步行 1 个月。在 1 个月时评估保留率、满意度和交互历史记录。在基线和干预后评估 6 分钟步行和步态速度。
55%的参与者为女性，平均年龄为 65.6 岁。研究完成时，保留率为 100%。患者对虚拟运动教练的满意度平均得分为 5.6/7（7 分表示非常满意）。交互历史记录显示，参与者在推荐的 30 天中平均登录了 25.4（7）天。每天步行的平均依从率为 85%。步态速度和 6 分钟步行测试均显著改善（P<0.05）。无不良事件报告。
久坐的帕金森病患者成功使用了计算机并与虚拟运动教练进行了交互。1 个月的保留率、满意度和日常步行依从率较高，且移动能力显著改善。
