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迟发性放射性脊髓病:正电子发射断层扫描/计算机断层扫描检查的鉴别诊断

Delayed radiation myelopathy: Differential diagnosis with positron emission tomography/computed tomography examination.

作者信息

Kadir Tufan, Sarica Feyzi Birol, Ozgur Kardes, Cekinmez Melih, Nur Altinors Mehmet

机构信息

Department of Neurosurgery, Baskent University Faculty of Medicine, Adana Education and Research Center, Adana, Turkey.

出版信息

Asian J Neurosurg. 2012 Oct;7(4):206-9. doi: 10.4103/1793-5482.106656.

DOI:10.4103/1793-5482.106656
PMID:23559989
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3613644/
Abstract

Myelopathy is a rare but serious complication of radiation therapy (RT). Radiation myelopathy is white matter damage to the spinal cord developed after a certain period of application of ionizing radiation. Factors such as radiation dose and time between applications affect the occurrence as well as the severity of myelopathy. In those patients, positron emission tomography/computed tomography examination has a very important role both in the diagnosis and in the differential diagnosis of lesions. In this case report, the case of progressive paraparesis, developed in a 52-year-old female patient operated with pulmonary mucinous cystadenocarcinoma diagnosis and who received chemotherapy and RT following surgery, has been reported.

摘要

脊髓病是放射治疗(RT)罕见但严重的并发症。放射性脊髓病是在一定时期应用电离辐射后发生的脊髓白质损伤。辐射剂量和两次照射之间的时间等因素会影响脊髓病的发生以及严重程度。在这些患者中,正电子发射断层扫描/计算机断层扫描检查在病变的诊断和鉴别诊断中都起着非常重要的作用。在本病例报告中,报道了一名52岁女性患者的病例,该患者因肺黏液性囊腺癌诊断接受手术,术后接受化疗和放疗,出现进行性双下肢轻瘫。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de16/3613644/b69c6caa66c3/AJNS-7-206-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de16/3613644/3ba6c19f34d6/AJNS-7-206-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de16/3613644/33f43aa6147f/AJNS-7-206-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de16/3613644/b69c6caa66c3/AJNS-7-206-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de16/3613644/3ba6c19f34d6/AJNS-7-206-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de16/3613644/33f43aa6147f/AJNS-7-206-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de16/3613644/b69c6caa66c3/AJNS-7-206-g003.jpg

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本文引用的文献

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Pathology of radiation myelopathy.放射性脊髓病的病理学
Neuropathology. 2001 Dec;21(4):247-65. doi: 10.1046/j.1440-1789.2001.00408.x.
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Radiation-induced myelopathy in long-term surviving metastatic spinal cord compression patients after hypofractionated radiotherapy: a clinical and magnetic resonance imaging analysis.大分割放疗后长期存活的转移性脊髓压迫患者的放射性脊髓病:一项临床和磁共振成像分析
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