乙醇和乙醛在离体灌流大鼠脑中的代谢 - Suppr

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Metabolism of ethanol and acetaldehyde by the isolated perfused rat brain.

作者信息

Mukherji B, Kashiki Y, Ohyanagi H, Sloviter H A

出版信息

J Neurochem. 1975 Apr;24(4):841-3.

PMID:235601

Abstract

摘要

相似文献

Metabolism of ethanol and acetaldehyde by the isolated perfused rat brain.乙醇和乙醛在离体灌流大鼠脑中的代谢

J Neurochem. 1975 Apr;24(4):841-3.

(2- 14 C) ethanol as a precursor of glutamine, glutamate, -aminobutyric acid and aspartate in hamster brain in vivo.（2-¹⁴C）乙醇作为谷氨酰胺、谷氨酸、γ-氨基丁酸和天冬氨酸在仓鼠脑内的体内前体。

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[Catabolism of gamma-hydroxybutyrate in rat brain].[大鼠脑中γ-羟基丁酸的分解代谢]

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Glutamate metabolism in the frog retina.青蛙视网膜中的谷氨酸代谢

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Relationship of brain ethanol metabolism to the hypnotic effect of ethanol. I: Studies in outbred animals.脑乙醇代谢与乙醇催眠作用的关系。I：远交系动物研究。

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D-beta-Hydrozybutyrate: a major precursor of amino acids in developing rat brain.

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Response of brain amino acid metabolism to ketosis.大脑氨基酸代谢对酮症的反应。

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引用本文的文献

Ethanol, not detectably metabolized in brain, significantly reduces brain metabolism, probably via action at specific GABA(A) receptors and has measureable metabolic effects at very low concentrations.乙醇在大脑中无法被检测到代谢，却能显著降低大脑代谢，可能是通过作用于特定的 GABA(A)受体，并在非常低的浓度下产生可测量的代谢作用。

J Neurochem. 2014 Apr;129(2):304-14. doi: 10.1111/jnc.12634. Epub 2013 Dec 18.

Metabolic products of [2-(13) C]ethanol in the rat brain after chronic ethanol exposure.慢性乙醇暴露后大鼠脑内 [2-(13)C]乙醇的代谢产物。

J Neurochem. 2013 Nov;127(3):353-64. doi: 10.1111/jnc.12405. Epub 2013 Sep 23.

Oxidation of ethanol in the rat brain and effects associated with chronic ethanol exposure.大鼠脑内乙醇的氧化及与慢性乙醇暴露相关的影响。

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14444-9. doi: 10.1073/pnas.1306011110. Epub 2013 Aug 12.

In vivo detection of intermediate metabolic products of [1-(13) C]ethanol in the brain using (13) C MRS.使用 (13) C MRS 在体内检测 [1-(13) C] 乙醇的中间代谢产物在大脑中的分布。

NMR Biomed. 2011 Nov;24(9):1054-62. doi: 10.1002/nbm.1653. Epub 2011 Feb 11.

Oxidation of ethanol in the brain and its consequences.大脑中乙醇的氧化及其后果。

Alcohol Res Health. 2006;29(4):266-73.

chi-ADH is the sole alcohol dehydrogenase isozyme of mammalian brains: implications and inferences.chi-ADH是哺乳动物大脑中唯一的乙醇脱氢酶同工酶：影响与推断。

Proc Natl Acad Sci U S A. 1985 Dec;82(24):8369-73. doi: 10.1073/pnas.82.24.8369.

Identiy of brain alcohol dehydrogenase with liver alcohol dehydrogenase.脑乙醇脱氢酶与肝乙醇脱氢酶的同一性。

Biochem J. 1976 Mar 1;153(3):561-6. doi: 10.1042/bj1530561.

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