Ha Nghi B, Trinh Huy N, Nguyen Trang T, Leduc Truong-Sinh, Bui Christopher, Ha Nghiem B, Wong Carrie R, Tran Anh Thu, Nguyen Mindie H
Pacific Health Foundation, San Jose, CA, USA.
J Cancer Educ. 2013 Jun;28(2):319-24. doi: 10.1007/s13187-013-0466-0.
Our goal is to examine the prevalence, risk factors, and disease knowledge of chronic hepatitis B (CHB) among Vietnamese Americans in California. We also examined treatment eligibility and linkage to care among patients who tested positive for CHB. We enrolled 717 subjects from ten different hepatitis B virus (HBV) screening events in five locations from January 2009 to June 2010 in California. HBV status was determined by hepatitis B surface antigen (HBsAg) and antibody. Data were collected by a 36-question survey. A total of 99 patients (13.8 %) had positive HBsAg, especially those aged 31-40 years (23.6 %), and 177 (24.7 %) were still susceptible to HBV infection. A significant proportion of those who were HBsAg positive or still susceptible reported a history of HBV vaccination (10 and 20 %, respectively). Following adjustments for age and sex, significant predictors for HBsAg positivity were lack of healthcare coverage (OR=2.4, p=0.004), having a family history of CHB (OR=2.1, p=0.009), and prior occupational exposure (OR=3.0, p=0.007). Of those who tested positive, 13.3 % met criteria for antiviral therapy, but none had been initiated on treatment. HBV prevalence in Vietnamese Americans in California was high (13.8 %), especially in those between 31 and 40 years of age. Patient disease and treatment knowledge was poor, as were follow-up and management of those found to have CHB and/or have indication for antiviral therapy.
我们的目标是调查加利福尼亚州越南裔美国人中慢性乙型肝炎（CHB）的患病率、风险因素及疾病知识。我们还对CHB检测呈阳性的患者的治疗资格及与医疗服务的联系进行了调查。2009年1月至2010年6月期间，我们在加利福尼亚州五个地点的十次不同的乙型肝炎病毒（HBV）筛查活动中招募了717名受试者。通过乙型肝炎表面抗原（HBsAg）和抗体确定HBV状态。通过一项包含36个问题的调查问卷收集数据。共有99名患者（13.8%）HBsAg呈阳性，尤其是年龄在31至40岁之间的患者（23.6%），177名患者（24.7%）仍易感染HBV。很大一部分HBsAg呈阳性或仍易感染的患者报告有HBV疫苗接种史（分别为10%和20%）。在对年龄和性别进行调整后，HBsAg阳性的显著预测因素包括缺乏医疗保险（比值比[OR]=2.4，p=0.004）、有CHB家族史（OR=2.1，p=0.009）以及既往职业暴露（OR=3.0，p=0.007）。在检测呈阳性的患者中，13.3%符合抗病毒治疗标准，但无人开始接受治疗。加利福尼亚州越南裔美国人中的HBV患病率较高（13.8%），尤其是在31至40岁的人群中。患者对疾病和治疗的了解较差，对那些被发现患有CHB和/或有抗病毒治疗指征的患者的随访和管理也较差。
