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用于韩牛(韩国本土牛)的鉴别 SNP 标记的开发。

Development of discrimination SNP markers for Hanwoo (Korean native cattle).

机构信息

Department of Genetic Epidemiology, SNP Genetics, Inc., Seoul, Republic of Korea.

出版信息

Meat Sci. 2013 Jul;94(3):355-9. doi: 10.1016/j.meatsci.2013.03.014. Epub 2013 Mar 16.

DOI:10.1016/j.meatsci.2013.03.014
PMID:23567136
Abstract

In the Korean meat market, the native cattle, Hanwoo beef, are preferred over imported beef and domestic Holstein beef despite its relatively high price. In order to hold the beef industry accountable and support consumers' right to know, correct beef-origin labeling is required. For this purpose, we developed 90 single-nucleotide polymorphism markers to discriminate between Hanwoo and other breeds including Holstein using 1602 cattle DNAs. The probability of discrimination was found to be 100% in a subsequent validation set consisting of 632 DNAs. Our study suggests that improved beef-origin discrimination can be achieved by using a combined genetic model that takes into account small genetic differences among a large number of markers. These markers could be useful for discriminating between Hanwoo and imported breeds including domestic Holsteins, and would contribute to the prevention of falsified beef origin.

摘要

在韩国的肉类市场上,尽管韩牛的价格相对较高,但它比进口牛肉和国产荷斯坦牛肉更受欢迎。为了让牛肉行业负责,并保障消费者的知情权,需要正确标注牛肉的来源。为此,我们开发了 90 个单核苷酸多态性标记物,利用 1602 头牛的 DNA 来区分韩牛和其他品种,包括荷斯坦牛。随后在一个由 632 个 DNA 组成的验证集中,发现了 100%的区分概率。我们的研究表明,通过使用一种综合的遗传模型,考虑到大量标记物之间的微小遗传差异,可以实现更好的牛肉来源区分。这些标记物可以用于区分韩牛和包括国产荷斯坦牛在内的进口品种,并有助于防止伪造的牛肉来源。

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