das Neves Carlos G, Ihlebæk Hanne M, Skjerve Eystein, Hemmingsen Willy, Li Hong, Tryland Morten
Section of Arctic Veterinary Medicine, Department of Food Safety and Infection Biology, The Norwegian School of Veterinary Science, Tromsø, Norway.
J Wildl Dis. 2013 Apr;49(2):261-9. doi: 10.7589/2012-07-185.
Malignant catarrhal fever (MCF) is caused by a group of gammaherpesviruses that primarily affect domestic and wild ruminants. Using competitive-inhibition enzyme-linked immunosorbent assay, we screened 3,339 apparently healthy, semidomesticated reindeer (Rangifer tarandus tarandus) from Finnmark County, Norway, sampled during slaughter. The overall antibody prevalence was 3.5% and varied among reindeer herding districts in Finnmark (0-6.7%), the largest reindeer herding region in Norway. The risk of exposure to gammaherpesvirus (i.e., seroconversion) was significantly higher for adult reindeer than it was for calves ≤1 yr, for reindeer in east Finnmark (3.8%) compared with west Finnmark (3.3%), and with increasing population density. No evidence of disease associated with this virus was detected in reindeer sampled for this study, but because samples were collected at slaughterhouses, one cannot discard the possibility of these events happening in the field. The low antibody prevalence could indicate occasional infection of reindeer with another ruminant gammaherpesvirus or the presence of a yet-unknown, specific, low-pathogenic reindeer gammaherpesvirus. Further studies should aim at characterizing the virus circulating in reindeer and address the potential clinical impact of this virus.
恶性卡他热（MCF）由一组主要感染家养和野生反刍动物的γ疱疹病毒引起。我们采用竞争抑制酶联免疫吸附测定法，对挪威芬马克郡3339头在屠宰时采样的看似健康的半家养驯鹿（Rangifer tarandus tarandus）进行了筛查。总体抗体阳性率为3.5%，在挪威最大的驯鹿放牧区芬马克的各个驯鹿放牧区之间有所不同（0 - 6.7%）。成年驯鹿感染γ疱疹病毒（即血清转化）的风险显著高于1岁及以下的幼鹿，东芬马克的驯鹿（3.8%）感染风险高于西芬马克的驯鹿（3.3%），且随着种群密度增加而升高。在本研究采样的驯鹿中未检测到与该病毒相关的疾病证据，但由于样本是在屠宰场采集的，不能排除这些事件在野外发生的可能性。低抗体阳性率可能表明驯鹿偶尔感染了另一种反刍动物γ疱疹病毒，或者存在一种未知的、特定的、低致病性的驯鹿γ疱疹病毒。进一步的研究应旨在鉴定在驯鹿中传播的病毒，并探讨该病毒的潜在临床影响。
