Norwegian Veterinary Institute, P.O. Box 750 Sentrum, NO-0106 Oslo, Norway.
Department of Arctic and Marine Biology, UiT The Arctic University of Norway, N-9019 Tromsø, Norway.
Viruses. 2020 Aug 11;12(8):876. doi: 10.3390/v12080876.
Gammaherpesvirus infections have been described in cervids worldwide, mainly the genera or . However, little is known about the gammaherpesviruses species infecting cervids in Norway and Fennoscandia. Blood samples from semi-domesticated ( = 39) and wild ( = 35) Eurasian tundra reindeer (), moose (, = 51), and red deer (, = 41) were tested using a panherpesvirus DNA polymerase (DPOL) PCR. DPOL-PCR-positive samples were subsequently tested for the presence of glycoprotein B (gB) gene. The viral DPOL gene was amplified in 28.2% (11/39) of the semi-domesticated reindeer and in 48.6% (17/35) of the wild reindeer. All moose and red deer tested negative. Additionally, gB gene was amplified in 4 of 11 semi-domesticated and 15 of 17 wild Eurasian reindeer DPOL-PCR-positive samples. All the obtained DPOL and gB sequences were highly similar among them, and corresponded to a novel gammaherpesvirus species, tentatively named , that seemed to belong to a genus different from and This is the first report of a likely host-specific gammaherpesvirus in semi-domesticated reindeer, an economic and cultural important animal, and in wild tundra reindeer, the lastpopulation in Europe. Future studies are required to clarify the potential impact of this gammaherpesvirus on reindeer health.
在世界各地的有蹄类动物中都有描述疱疹病毒感染，主要是属或。然而，对于感染挪威和芬诺斯堪的亚有蹄类动物的疱疹病毒种知之甚少。使用泛疱疹病毒 DNA 聚合酶（DPOL）PCR 检测了 39 只半驯化（=39）和 35 只野生（=35）欧亚驯鹿（）、驼鹿（，=51）和马鹿（，=41）的血液样本。随后，对 DPOL-PCR 阳性样本进行糖蛋白 B（gB）基因检测。在 28.2%（11/39）的半驯化驯鹿和 48.6%（17/35）的野生驯鹿中扩增出了病毒 DPOL 基因。所有驼鹿和马鹿均呈阴性。此外，在 11 个半驯化和 17 个野生欧亚驯鹿 DPOL-PCR 阳性样本中的 4 个和 15 个中扩增出了 gB 基因。所有获得的 DPOL 和 gB 序列在它们之间高度相似，与一种新型的疱疹病毒种，暂定名为，似乎属于与和不同的属。这是首例在半驯化驯鹿（一种经济和文化上重要的动物）和野生苔原驯鹿（欧洲最后一个种群）中发现的可能宿主特异性疱疹病毒的报告。需要进一步的研究来阐明这种疱疹病毒对驯鹿健康的潜在影响。
