Mak Jenson C S, Lattouf Ihab, Narushevich Alexei, Lai Charles, O'Rourke Fintan, Shen Qing, Chan Daniel K Y, Cameron Ian D
Department of Geriatric Medicine, Northern Sydney Central Coast Area Health Service, Gosford Hospital, NSW, Australia ; Department of General Medicine, Mater Hospital, Sydney, NSW, Australia ; Rehabilitation Studies Unit, Sydney Medical School, University of Sydney, NSW, Australia.
Geriatr Orthop Surg Rehabil. 2011 Mar;2(2):45-50. doi: 10.1177/2151458510394655.
To correlate analgesia use among patients with hip fracture requiring surgery with hip fracture subtype, cognitive status, and type of surgery in the postacute period.
Prospective review of patients with hip fractures requiring surgical intervention. A total of 415 patients (mean age: 81.2 ± 9.1 years, 74.3% women) presented with 195 subcapital fractures (39 undisplaced, 156 displaced) and 220 trochanteric fractures (136 stable, 84 unstable) requiring surgery.
Inpatient orthopedic units in 4 Australian hospitals.
The primary outcome measures were mean analgesia usage (oral morphine equivalent) for 4 defined time intervals and total amount 36 hours following surgery.
Patients with subtrochanteric fractures required more analgesia compared with displaced-subcapital, undisplaced-subcapital, basicervical, stable-pertrochanteric, and unstable-pertrochanteric fractures in the 24 to 36 hours following operation (24.7 vs 11.3 vs 8.8 vs 12.1 vs 7.6 vs 9.7, P = .001). Total analgesia requirements were higher in patients treated with an intramedullary nail, increasing by 1.3- to 3.3-fold in the 36 hours postsurgery. Patients with cognitive impairment utilized markedly less analgesia at all time periods measured. At 24 to 36 hours, higher levels of analgesia were noted in patients with higher premorbid level of mobility (P = .015) and activities of daily living function (P = .007).
Important differences in utilization of analgesia following hip fracture across readily defined clinical groups exist. Proactive pain management for those with cognitive impairment, certain hip fracture subtypes, and surgical procedures may enable early functional mobility and other activities.
将需要手术治疗的髋部骨折患者的镇痛药物使用情况与髋部骨折亚型、认知状态以及急性期后的手术类型进行关联分析。
对需要手术干预的髋部骨折患者进行前瞻性研究。共有415例患者(平均年龄:81.2±9.1岁,女性占74.3%),其中195例为股骨头下骨折(39例无移位,156例移位),220例为转子间骨折(136例稳定,84例不稳定),均需要手术治疗。
澳大利亚4家医院的骨科住院病房。
主要结局指标为4个规定时间段内的平均镇痛药物使用量(口服吗啡当量)以及术后36小时的总量。
与移位型股骨头下骨折、无移位型股骨头下骨折、基底骨折、稳定型转子间骨折和不稳定型转子间骨折相比,转子下骨折患者在术后24至36小时需要更多的镇痛药物(24.7 vs 11.3 vs 8.8 vs 12.1 vs 7.6 vs 9.7,P = 0.001)。采用髓内钉治疗的患者总镇痛需求更高,术后36小时增加了1.3至3.3倍。在所有测量时间段内,认知障碍患者使用的镇痛药物明显较少。在24至36小时,术前活动能力较高(P = 0.015)和日常生活功能较高(P = 0.007)的患者镇痛药物使用水平较高。
在易于定义的临床组中,髋部骨折后镇痛药物的使用存在重要差异。对认知障碍患者、某些髋部骨折亚型患者和手术患者进行积极的疼痛管理可能有助于早期功能活动和其他活动。