Belghiti J, Coulm B, Kayem G, Blondel B, Deneux-Tharaux C
Inserm UMR S953, unité de recherche épidémiologique en santé périnatale et santé des femmes et des enfants, maternité Port-Royal, 53, avenue de l'Observatoire, 75014 Paris, France; Université Pierre-et-Marie-Curie Paris 6, 75005 Paris, France.
J Gynecol Obstet Biol Reprod (Paris). 2013 Nov;42(7):662-70. doi: 10.1016/j.jgyn.2013.02.011. Epub 2013 Apr 6.
To estimate the frequency of oxytocin administration during labor, in all women in labor, in low-risk women, and in women with a previous cesarean delivery. Our objectives were also to identify characteristics of women and of maternity units associated with this practice in France.
Analysis of the 2010 French Perinatal Survey data (n=14,681 women who delivered in continental France). The frequency of oxytocin administration during labor was estimated in all women in labor (n=12,845) and in low-risk women (n=9798). The independent associations between oxytocin administration during labor and characteristics of women and units were quantified with multivariate logistic regression modeling.
Sixty-four percent of laboring women received oxytocin during labor, and 58% of women with a spontaneous onset of labor. In the population of low-risk women with spontaneous labor and epidural, nulliparity and over-weight, as well as the private status and small size of the maternity unit, were independently associated with a more frequent administration of oxytocin during labor.
Oxytocin administration during labor is very frequent in France, probably beyond classical indications.
评估所有分娩女性、低风险女性以及有剖宫产史女性在分娩期间使用缩宫素的频率。我们的目的还包括确定法国与这种做法相关的女性及产科单位的特征。
对2010年法国围产期调查数据（在法国大陆分娩的14,681名女性）进行分析。估计所有分娩女性（12,845名）和低风险女性（9798名）在分娩期间使用缩宫素的频率。通过多变量逻辑回归模型量化分娩期间使用缩宫素与女性及产科单位特征之间的独立关联。
64%的分娩女性在分娩期间接受了缩宫素治疗，58%的自然发动分娩女性接受了缩宫素治疗。在自然发动分娩且采用硬膜外麻醉的低风险女性人群中，初产、超重以及产科单位的私立性质和规模较小与分娩期间更频繁使用缩宫素独立相关。
在法国，分娩期间使用缩宫素的情况非常普遍，可能超出了传统适应症。
