通过反射式共聚焦显微镜对健康口腔黏膜进行体内表征：光学活检的转化研究。
In vivo characterization of healthy oral mucosa by reflectance confocal microscopy: a translational research for optical biopsy.
作者信息
Contaldo Maria, Agozzino Marina, Moscarella Elvira, Esposito Salvatore, Serpico Rosario, Ardigò Marco
机构信息
Department of Odontostomatological, Orthodontic and Surgical Sciences, Second University of Naples, Naples, Italy.
出版信息
Ultrastruct Pathol. 2013 Apr;37(2):151-8. doi: 10.3109/01913123.2013.776656.
PURPOSE
To characterize in vivo microscopic features of healthy oral mucosa by noninvasive, real-time reflectance confocal microscopy (RCM).
MATERIAL AND METHODS
One hundred healthy mucosal sites (38 lips, 24 cheeks, 10 gingivae, and 28 tongues) from 50 randomly selected volunteers were imaged by a commercially available in vivo RCM (Vivascope3000, Lucid, Rochester, NY). Morphological results were described and correlated with conventional histology.
RESULTS
Specific microscopic parameters (cellular morphology, anatomical structures features, architectural patterns) were identified by RCM for each mucosal site.
CONCLUSIONS
RCM features reproducibility in different mucosal sites and subjects, which suggests that RCM can be an adjunct tool for clinical management in stomatology.
目的
通过非侵入性实时反射共聚焦显微镜（RCM）对健康口腔黏膜的体内微观特征进行表征。
材料与方法
从50名随机选择的志愿者身上选取100个健康黏膜部位（38个唇部、24个颊部、10个牙龈和28个舌部），使用市售的体内RCM（Vivascope3000，Lucid，罗切斯特，纽约）进行成像。描述形态学结果并与传统组织学进行关联。
结果
RCM为每个黏膜部位确定了特定的微观参数（细胞形态、解剖结构特征、结构模式）。
结论
RCM在不同黏膜部位和受试者中具有可重复性，这表明RCM可以成为口腔医学临床管理的辅助工具。
Zotero 插件