在 3 特斯拉下对正常人体子宫进行弥散张量成像（DTI）：不同子宫层之间 DTI 参数的比较。
Diffusion tensor imaging (DTI) of the normal human uterus in vivo at 3 tesla: comparison of DTI parameters in the different uterine layers.
机构信息
Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
出版信息
J Magn Reson Imaging. 2013 Dec;38(6):1494-500. doi: 10.1002/jmri.24114. Epub 2013 Apr 10.
PURPOSE
To investigate the differences in the fiber architecture and related diffusion tensor imaging (DTI) parameters among different uterine layers of the normal human uterus in vivo at 3 Tesla (T).
MATERIALS AND METHODS
DTI of the uterus was performed for nine healthy women of reproductive age on a 3T scanner. A volume of interest (VOI) was drawn for the outer myometrium (OM), junctional zone (JZ), and endometrium (EM). Apparent diffusion coefficient (ADC), fractional anisotropy (FA), and maximum fiber length were compared using paired Student's t-tests. Fibers were classified into four groups and were visually evaluated.
RESULTS
ADC (×10(-3) mm(2) /s) was highest for OM (1.12), followed by EM (0.97) and JZ (0.83) (OM versus JZ, P < 0.0001; JZ versus EM, P = 0.0001; OM versus EM, P = 0.0057). FA was highest for JZ (0.297), followed by OM (0.257) and EM (0.186) (OM versus JZ, P = 0.0002; JZ versus EM, P < 0.0001; OM versus EM, P < 0.0001). Fibers were longest in OM (42.0 mm), followed by JZ (34.2 mm) and EM (20.0 mm). Circularly oriented fibers were observed in 69% in OM and in 70% in JZ.
CONCLUSION
DTI of the uterus in vivo revealed layer-wise differences in the microstructure of the uterus.
目的
在 3.0T 场强下，研究活体正常子宫不同子宫层的纤维结构及其相关弥散张量成像（DTI）参数的差异。
材料与方法
在 3.0T 扫描仪上对 9 名育龄期健康女性的子宫进行 DTI 检查。在子宫的外层肌层（OM）、结合区（JZ）和子宫内膜（EM）分别绘制感兴趣区（VOI）。采用配对学生 t 检验比较表观扩散系数（ADC）、各向异性分数（FA）和最大纤维长度。对纤维进行分类，并进行视觉评估。
结果
ADC（×10(-3) mm(2) /s）在 OM 中最高（1.12），其次是 EM（0.97）和 JZ（0.83）（OM 与 JZ，P < 0.0001；JZ 与 EM，P = 0.0001；OM 与 EM，P = 0.0057）。FA 在 JZ 中最高（0.297），其次是 OM（0.257）和 EM（0.186）（OM 与 JZ，P = 0.0002；JZ 与 EM，P < 0.0001；OM 与 EM，P < 0.0001）。OM 中的纤维最长（42.0mm），其次是 JZ（34.2mm）和 EM（20.0mm）。在 OM 中观察到 69%的环形纤维，在 JZ 中观察到 70%的环形纤维。
结论
活体子宫的 DTI 显示了子宫不同层微观结构的分层差异。
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