猴口服葡萄球菌肠毒素B致吐的机制（38553）
Mechanisms of oral staphylococcal enterotoxin B-induced emesis in the monkey (38553).
作者信息
Elwell M R, Liu C T, Spertzel R O, Beisel W R
出版信息
Proc Soc Exp Biol Med. 1975 Feb;148(2):424-7. doi: 10.3181/00379727-148-38553.
PMID:235765
Abstract
Vomition is the most consistent response to oral SEB challenge in the monkey. The technique of cross-circulation clearly differentiates local neural phenomenon from humoral mechanisms. Our results support the theory that SED-induced vomition follows stimulation of local neural receptors in the gut. The evidence indicates no significant amount of enterotoxin absorption or stimulation of vomition by any centrally acting humoral mechanism.
摘要
呕吐是猴子口服SEB（葡萄球菌肠毒素B）激发试验中最一致的反应。交叉循环技术清楚地将局部神经现象与体液机制区分开来。我们的结果支持这样一种理论，即SED（推测有误，可能是SEB）诱导的呕吐是由肠道局部神经受体受刺激引起的。证据表明没有大量的肠毒素吸收，也没有任何中枢作用的体液机制刺激呕吐。
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