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本文引用的文献

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Validation of bedside methods in evaluation of diabetic peripheral neuropathy.床边方法评估糖尿病周围神经病变的验证。
Indian J Med Res. 2011 Jun;133(6):645-9.
2
Screening and prevalence of peripheral neuropathy in type 2 diabetic outpatients: a randomized multicentre survey in 12 city hospitals of China.2 型糖尿病门诊患者周围神经病变的筛查和患病率:中国 12 家城市医院的随机多中心调查。
Diabetes Metab Res Rev. 2010 Sep;26(6):481-9. doi: 10.1002/dmrr.1107.
3
Small-fibre involvement in diabetic patients with neuropathic foot pain.小纤维受累在患有神经性足部疼痛的糖尿病患者中。
Diabet Med. 2008 Jun;25(6):692-9. doi: 10.1111/j.1464-5491.2008.02446.x.
4
Neuropathy: mobility and quality of life.神经病变:活动能力与生活质量。
Diabetes Metab Res Rev. 2008 May-Jun;24 Suppl 1:S45-51. doi: 10.1002/dmrr.856.
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A cohort study of people with diabetes and their first foot ulcer: the role of depression on mortality.一项关于糖尿病患者及其首次足部溃疡的队列研究:抑郁症对死亡率的影响。
Diabetes Care. 2007 Jun;30(6):1473-9. doi: 10.2337/dc06-2313. Epub 2007 Mar 15.
6
Validation of the Infectious Diseases Society of America's diabetic foot infection classification system.美国传染病学会糖尿病足感染分类系统的验证
Clin Infect Dis. 2007 Feb 15;44(4):562-5. doi: 10.1086/511036. Epub 2007 Jan 17.
7
The incidence and risks of failure to heal after lower extremity amputation for the treatment of diabetic neuropathic foot ulcer.糖尿病性神经性足溃疡下肢截肢术后不愈合的发生率及风险
J Foot Ankle Surg. 2006 Nov-Dec;45(6):366-74. doi: 10.1053/j.jfas.2006.08.002.
8
Predictors, consequences and costs of diabetes-related lower extremity amputation complicating type 2 diabetes: the Fremantle Diabetes Study.2型糖尿病合并糖尿病相关下肢截肢的预测因素、后果及成本:弗里曼特尔糖尿病研究
Diabetologia. 2006 Nov;49(11):2634-41. doi: 10.1007/s00125-006-0431-0. Epub 2006 Sep 26.
9
Validation of Michigan neuropathy screening instrument for diabetic peripheral neuropathy.密歇根糖尿病周围神经病变筛查工具的验证
Clin Neurol Neurosurg. 2006 Jul;108(5):477-81. doi: 10.1016/j.clineuro.2005.08.003. Epub 2005 Sep 16.
10
Global prevalence of diabetes: estimates for the year 2000 and projections for 2030.全球糖尿病患病率:2000年的估计数及2030年的预测数。
Diabetes Care. 2004 May;27(5):1047-53. doi: 10.2337/diacare.27.5.1047.

初级卫生保健机构中不同筛查试验用于诊断糖尿病周围神经病变的比较

Comparison of different screening tests for diagnosis of diabetic peripheral neuropathy in Primary Health Care setting.

作者信息

Al-Geffari Metab

机构信息

College of Medicine, Qassim University.

出版信息

Int J Health Sci (Qassim). 2012 Jun;6(2):127-34. doi: 10.12816/0005988.

DOI:10.12816/0005988
PMID:23580893
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3616942/
Abstract

BACKGROUND

DPN is an important complication and contributes to the morbidity of diabetes mellitus. Evidence indicates early detection of DPN results in fewer foot ulcers and amputations.

OBJECTIVE

The purpose of this study was to compare different screening tests in the detection of DPN in primary care setting.

METHODOLOGY

It is a cross-sectional study in a random sample (N = 242) of type 2 diabetes mellitus participants at primary care setting. Different screening tests for detecting DPN such as Michigan Neuropathy Screening Instrument (MNSI), Semmes-Weinstein Monofilament (SWM), vibration sensation and ankle reflex were performed for each patient and compare between them.

RESULTS

45% of the participant had DPN based on MNSI, The detection rate using the 128-Hz tuning fork and 10-g SWM was nearly same (32.6 & 31.4%) respectively and significantly higher than ankle reflexes (23.1%). Although, the prevalence of DPN determined by the combined two tests (38.79%) was higher than that through the single test.

CONCLUSION

this study showed different results of DPN screening tests, even in the same group of patients. However there was a significant correlation between them. 128-Hz tuning fork and 10-g SWM monofilament would appear to be an appropriate, cheap and easy to use tool for identifying patients at risk of having neuropathy in primary care setting.

摘要

背景

糖尿病周围神经病变(DPN)是糖尿病的一种重要并发症,会增加糖尿病的发病率。有证据表明,早期发现DPN可减少足部溃疡和截肢的发生。

目的

本研究旨在比较在基层医疗环境中检测DPN的不同筛查试验。

方法

这是一项横断面研究,对基层医疗环境中2型糖尿病患者的随机样本(N = 242)进行研究。对每位患者进行了不同的DPN检测筛查试验,如密歇根神经病变筛查工具(MNSI)、Semmes-Weinstein单丝检查(SWM)、振动觉和踝反射,并对这些试验进行比较。

结果

根据MNSI,45%的参与者患有DPN。使用128赫兹音叉和10克SWM的检测率分别接近(32.6%和31.4%),且显著高于踝反射(23.1%)。尽管如此,两项联合试验确定的DPN患病率(38.79%)高于单项试验。

结论

本研究表明,即使在同一组患者中,DPN筛查试验的结果也有所不同。然而,它们之间存在显著相关性。128赫兹音叉和10克SWM单丝似乎是在基层医疗环境中识别有神经病变风险患者的合适、廉价且易于使用的工具。