Darivemula Surendra, Nagoor Khadervali, Patan Shakeer Khan, Reddy N Bayapa, Deepthi C Sravana, Chittooru Chandra Sekhar
Department of Community Medicine, Apollo Institute of Medical Sciences and Research, Chittoor, Andhra Pradesh, India.
Indian J Community Med. 2019 Apr-Jun;44(2):88-91.
Diabetic peripheral neuropathy (DPN) is a well-known microvascular complication of type 2 diabetes mellitus attributed to chronic hyperglycemia and is defined as the presence of peripheral nerve dysfunction after exclusion of other causes.
This was a multicentric facility-based cross-sectional study with the objectives to assess the sociodemographic and economic status of the participants, to estimate the prevalence of the DPN using the screening methods, and to see the association with other factors. A predesigned semi-structured questionnaire, Semmes-Weinstein 10-g monofilament test, ankle reflexes, and vibration perception threshold test was used for the data collection and blood sugars levels were taken from the recent laboratory report.
Among 336, 202 (60.1%) were male and 134 (39.9%) were female. The prevalence of the DPN was 39.3% among them 28.9% in males and 10.4% in females, respectively. The other determinants of the participants, 264 (78.6%) had the Glycated hemoglobin (HbA1c) >7, 205 (61%) had a burning foot sensation, 124 (36.9%) of them were had numbness of the foot, almost 50% of them had pricking sensation in the foot and more than one-third (130) of them had callosity over foot.
The study showed the severity of DPN was significantly associated with age, sex, duration of diabetes, HbA1c value, hypertension, and body mass index.
糖尿病周围神经病变（DPN）是2型糖尿病一种广为人知的微血管并发症，归因于慢性高血糖，其定义为排除其他病因后存在周围神经功能障碍。
这是一项基于多中心机构的横断面研究，目的是评估参与者的社会人口统计学和经济状况，使用筛查方法估计DPN的患病率，并观察其与其他因素的关联。采用预先设计的半结构化问卷、Semmes-Weinstein 10克单丝试验、踝反射和振动觉阈值测试进行数据收集，血糖水平取自近期实验室报告。
在336名参与者中，202名（60.1%）为男性，134名（39.9%）为女性。DPN的患病率为39.3%，其中男性为28.9%，女性为10.4%。其他参与者的决定因素包括，264名（78.6%）糖化血红蛋白（HbA1c）>7，205名（61%）有足部烧灼感，124名（36.9%）足部麻木，近50%足部有刺痛感，超过三分之一（130名）足部有胼胝。
研究表明，DPN的严重程度与年龄、性别、糖尿病病程、HbA1c值、高血压和体重指数显著相关。
