Department of Plastic and Reconstructive Surgery, Division of Anatomic and Surgical Pathology, Yokohama City University Hospital, Yokohama, Japan.
Australas J Dermatol. 2013 May;54(2):e46-9. doi: 10.1111/j.1440-0960.2011.00857.x. Epub 2012 Jan 19.
Endocrine mucin-producing sweat gland carcinoma (EMPSGC) has recently been recognised as a low-grade carcinoma that almost always occurs on the eyelid. This carcinoma is very rare, with only 20 cases (including the present one) having been reported in the literature. EMPSGC is frequently found in association with invasive mucinous carcinoma. While EMPSGC treatments consist of a complete surgical removal, there has been no consensus regarding the surgical margin. Therefore, reports on surgical management of EMPSGC may potentially provide important therapeutic information. Here, we present a case of a 74-year-old man with EMPSGC of the eyelid that repeatedly recurred despite surgical treatments at another institution. After referral to our department, the patient underwent tumour excision. However, the specimen revealed a positive surgical margin and thus, he subsequently underwent a wider excision. There has been no sign of tumour recurrence or metastasis 6 months after his last operation. This article reviews the current literature and discusses the surgical management of EMPSGC.
内分泌黏液性汗腺癌（EMPSGC）最近被认为是一种低级别癌，几乎总是发生在眼睑上。这种癌症非常罕见，文献中仅报告了 20 例（包括本例）。EMPSGC 常与浸润性黏液癌相关。EMPSGC 的治疗包括完全手术切除，但对于手术切缘尚无共识。因此，关于 EMPSGC 手术治疗的报道可能提供重要的治疗信息。在此，我们报告了一例 74 岁男性眼睑 EMPSGC 病例，尽管在另一机构进行了手术治疗，但仍反复复发。转至我们科室后，患者接受了肿瘤切除术。然而，标本显示切缘阳性，因此他随后进行了更广泛的切除。末次手术后 6 个月，未见肿瘤复发或转移迹象。本文复习了目前的文献，并讨论了 EMPSGC 的手术治疗。
