Groebe G, Marsch W C, Holzmann H
Zentrum der Dermatologie und Venerologie, Johann Wolfgang Goethe-Universität Frankfurt am Main.
Hautarzt. 1990 Apr;41(4):226-8.
The width of a Woronoff ring is thought to be constant and independent of the diameter of the lesion. Clinical observations have allowed us to demonstrate that this is true only for lesions of a certain minimum size or greater. It is suggested that the paleness within the ring is caused by diffusion of a mediator from the psoriatic plaque into its environment. A mathematical model is formulated, and it is shown that clinical observations are consistent with the pathogenetic hypothesis. In addition, the mathematical model is used to derive some properties of the hypothetical mediator.
沃罗诺夫环的宽度被认为是恒定的,且与病变的直径无关。临床观察使我们得以证明,只有对于一定最小尺寸或更大尺寸的病变,情况才是如此。有人提出,环内的苍白是由一种介质从银屑病斑块扩散到其周围环境所致。构建了一个数学模型,结果表明临床观察结果与发病机制假说相符。此外,该数学模型还用于推导这种假设介质的一些特性。