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青少年高血压危象:疑似肾血管性高血压的评估

Hypertensive crises in the adolescent: evaluation of suspected renovascular hypertension.

作者信息

Wijaya Indra, Siregar Parlindungan

机构信息

Department of Internal Medicine. Faculty of Medicine, University of Indonesia - Cipto Mangunkusumo Hospital. Jl. Diponegoro no. 71, Jakarta 10431, Indonesia.

出版信息

Acta Med Indones. 2013 Jan;45(1):49-54.

Abstract

Hypertensive crises can be divided into two categories as hypertensive emergency and hypertensive urgency. Most authorities have defined hypertensive emergency as a situation that requires immediate reduction in blood pressure (BP) with parenteral agents because of acute or progressive target organ damage, whereas hypertensive urgency is a situation with markedly elevated BP but without severe symptoms or progressive target organ damage, wherein the BP should be reduced within hours, often with oral agents. Adolescent with hypertension should be suspected of having renovascular hypertension in spite of other causes. This case is presenting a 16-year-old boy with hypertensive crises due to suspected renovascular hypertension. His blood pressure was 240/120 at admission with hypertensive retinopathy grade III and there was increase in creatinine after administering ACE-inhibitor but his renal arteriography revealed normal, other physical examination and laboratory findings was normal. Regarding these findings, the conclusion was this patient got essential hypertension. As many hypertensive crises occur in any ages, clinicians should aware the possibility of renovascular hypertension in young patients with hypertensive crises. An early detection and urgent treatment are needed to prevent the implication of progressive target organ damage.

摘要

高血压急症可分为高血压紧急状态和高血压次急症两类。大多数权威机构将高血压紧急状态定义为因急性或进行性靶器官损害而需要立即用胃肠外药物降低血压(BP)的情况,而高血压次急症是指血压明显升高但无严重症状或进行性靶器官损害的情况,此时血压应在数小时内降低,通常使用口服药物。尽管有其他病因,患有高血压的青少年仍应怀疑患有肾血管性高血压。本病例介绍了一名16岁男孩因疑似肾血管性高血压而出现高血压急症。他入院时血压为240/120,患有III级高血压性视网膜病变,使用血管紧张素转换酶抑制剂(ACE-inhibitor)后肌酐升高,但他的肾动脉造影显示正常,其他体格检查和实验室检查结果均正常。基于这些发现,结论是该患者患有原发性高血压。由于任何年龄段都可能发生许多高血压急症,临床医生应意识到年轻高血压急症患者患肾血管性高血压的可能性。需要早期检测和紧急治疗以防止进行性靶器官损害的发生。

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