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突发视力减退作为慢性肾衰竭的首发症状

Sudden Visual Deterioration as the First Symptom of Chronic Kidney Failure.

作者信息

Pociej-Marciak Weronika, Karska-Basta Izabella, Kuźniewski Marek, Kubicka-Trząska Agnieszka, Romanowska-Dixon Bożena

机构信息

Departments of Ophthalmology, Jagiellonian University Medical College, Kraków, Poland.

Nephrology, Jagiellonian University Medical College, Kraków, Poland.

出版信息

Case Rep Ophthalmol. 2015 Nov 28;6(3):394-400. doi: 10.1159/000442182. eCollection 2015 Sep-Dec.

Abstract

PURPOSE

We report here a unique case of a sudden loss of vision as the first symptom of an advanced chronic nephropathy.

METHODS AND RESULTS

A 25-year-old man was referred to the Department of Ophthalmology with sudden visual deterioration presumptively diagnosed as bilateral retinitis. The patient had never been under any medical care before and had never had any clinical signs of any chronic disease. He underwent an ophthalmic examination with optical coherence tomography (OCT). Based on the clinical features, OCT scans and systemic blood pressure (BP) assessment (225/145 mm Hg), the patient was definitely diagnosed with hypertensive retinopathy and choroidopathy due to hypertensive crisis. After urgent diagnostic procedures, the patient was diagnosed with a chronic kidney disease at stage 5 in the course of chronic glomerulonephritis. Immediately, a renal replacement therapy was started and the patient was qualified for renal transplantation.

CONCLUSION

Adolescents with an unclear picture of retinal lesions, who have neither a history nor clinical signs of a systemic disease, should undergo careful systemic screening with BP assessment. A sudden deterioration of vision may be the first symptom of a previously undiagnosed severe systemic disease (very rare chronic) that requires immediate treatment.

摘要

目的

我们在此报告一例独特病例,即视力突然丧失作为晚期慢性肾病的首发症状。

方法与结果

一名25岁男性因突然视力恶化被转诊至眼科,初步诊断为双侧视网膜炎。该患者此前从未接受过任何医疗护理,也从未有过任何慢性疾病的临床症状。他接受了光学相干断层扫描(OCT)眼科检查。根据临床特征、OCT扫描及全身血压(BP)评估(225/145mmHg),该患者被明确诊断为高血压性视网膜病变和高血压危象所致脉络膜病变。经过紧急诊断程序,患者被诊断为慢性肾小球肾炎病程中的5期慢性肾脏病。随即开始肾脏替代治疗,患者符合肾移植条件。

结论

对于视网膜病变情况不明、既无全身疾病病史也无临床症状的青少年,应通过血压评估进行仔细的全身筛查。视力突然恶化可能是先前未诊断出的严重全身疾病(非常罕见的慢性病)的首发症状,需要立即治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9187/4777964/7b70ac442836/cop-0006-0394-g01.jpg

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