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一例快速进展的致命性抗精神病药恶性综合征病例。

A rapidly progressing lethal case of neuroleptic malignant syndrome.

作者信息

Lenler-Petersen P, Hansen B D, Hasselstrøm L

机构信息

Department of Anesthesiology, Randers Centralsygehus, Denmark.

出版信息

Intensive Care Med. 1990;16(4):267-8. doi: 10.1007/BF01705164.

DOI:10.1007/BF01705164
PMID:2358561
Abstract

A fast progressing lethal case of neuroleptic malignant syndrome (NMS) complicated by disseminated intravascular coagulation (DIC) is presented. The fulminant course is infrequent and relates NMS to malignant hyperthermia. Muscular relaxation in combination with fluid load dramatically decreased the temperature, but the catastrophic course of this case was so advanced that the currently recommended treatment of NMS was impossible.

摘要

本文报告了一例快速进展的致死性神经阻滞剂恶性综合征(NMS),并伴有弥散性血管内凝血(DIC)。暴发性病程并不常见,且将NMS与恶性高热联系起来。肌肉松弛联合液体负荷显著降低了体温,但该病例的灾难性病程进展过快,以至于目前推荐的NMS治疗方法已无法实施。

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1
A rapidly progressing lethal case of neuroleptic malignant syndrome.一例快速进展的致命性抗精神病药恶性综合征病例。
Intensive Care Med. 1990;16(4):267-8. doi: 10.1007/BF01705164.
2
[A successfully treated parkinsonian patient with neuroleptic malignant syndrome complicated by status epilepticus and disseminated intravascular coagulation].[一名成功治疗的帕金森病患者,并发神经阻滞剂恶性综合征、癫痫持续状态和弥散性血管内凝血]
Rinsho Shinkeigaku. 1999 Jun;39(6):653-7.
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Successful treatment of a complicated case of neuroleptic malignant syndrome.成功治疗一例复杂的抗精神病药恶性综合征病例。
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Neuroleptic malignant syndrome presenting as adult respiratory distress syndrome and disseminated intravascular coagulation.以成人呼吸窘迫综合征和弥散性血管内凝血为表现的抗精神病药恶性综合征
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[Successful treatment of levodopa-induced neuroleptic malignant syndrome (NMS) with disseminated intravascular coagulation (DIC) in a patient with Parkinson's disease].[帕金森病患者左旋多巴诱发的伴有弥散性血管内凝血(DIC)的神经精神恶性综合征(NMS)的成功治疗]
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Successful treatment of levodopa-induced neuroleptic malignant syndrome (NMS) and disseminated intravascular coagulation (DIC) in a patient with Parkinson's disease.成功治疗一名帕金森病患者的左旋多巴诱发的神经精神性恶性综合征(NMS)和弥散性血管内凝血(DIC)。
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Neuroleptic malignant syndrome.抗精神病药恶性综合征
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引用本文的文献

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A fatal case of fulminant neuroleptic malignant syndrome: A case report.一例暴发性抗精神病药恶性综合征致死病例:病例报告
PCN Rep. 2023 Jan 23;2(1):e75. doi: 10.1002/pcn5.75. eCollection 2023 Mar.
2
Neuroleptic malignant syndrome: a review for neurohospitalists.抗精神病药恶性综合征:给神经科住院医师的综述
Neurohospitalist. 2011 Jan;1(1):41-7. doi: 10.1177/1941875210386491.
3
Neuroleptic malignant syndrome. Recognition, prevention and management.抗精神病药恶性综合征。识别、预防与处理

本文引用的文献

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Neuroleptic malignant syndrome: successful treatment with dantrolene and bromocriptine.
Ann Neurol. 1983 Jul;14(1):89-90. doi: 10.1002/ana.410140117.
2
Neuroleptic malignant syndrome and malignant hyperthermia.
Lancet. 1983 Jan 29;1(8318):244. doi: 10.1016/s0140-6736(83)92620-x.
3
Neuroleptic malignant syndrome. Successful treatment with bromocriptine.抗精神病药恶性综合征。溴隐亭治疗成功。
JAMA. 1983 Jan 21;249(3):386-8.
4
Drug Saf. 1998 Jul;19(1):73-82. doi: 10.2165/00002018-199819010-00006.
Neuroleptic malignant syndrome: a pathogenetic role for dopamine receptor blockade?
抗精神病药恶性综合征:多巴胺受体阻断的发病机制作用?
Neurology. 1981 Feb;31(2):132-7. doi: 10.1212/wnl.31.2.132.
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The neuroleptic malignant syndrome.神经阻滞剂恶性综合征
J Clin Psychiatry. 1980 Mar;41(3):79-83.
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Hyperpyrexia following psychotropic drug overdose.精神药物过量后出现的高热
Anaesthesia. 1985 Nov;40(11):1097-9. doi: 10.1111/j.1365-2044.1985.tb10609.x.
7
Fatal disseminated intravascular coagulation following a monoamine oxidase inhibitor/tricyclic interaction.单胺氧化酶抑制剂与三环类药物相互作用后发生致命性弥散性血管内凝血。
Anaesthesia. 1987 Jul;42(7):760-3. doi: 10.1111/j.1365-2044.1987.tb05324.x.
8
Malignant hyperthermia susceptibility in neuroleptic malignant syndrome.
Anesthesiology. 1987 Jul;67(1):20-5. doi: 10.1097/00000542-198707000-00004.
9
Neuroleptic malignant syndrome presenting as adult respiratory distress syndrome and disseminated intravascular coagulation.以成人呼吸窘迫综合征和弥散性血管内凝血为表现的抗精神病药恶性综合征
South Med J. 1988 Apr;81(4):543-5. doi: 10.1097/00007611-198804000-00038.
10
Fatal thermal injury.致命性热损伤。
Med J Aust. 1989 Feb 20;150(4):215-7. doi: 10.5694/j.1326-5377.1989.tb136431.x.