Weber B, Smith J P, Briscoe W A, Friedman S A, King T K
Am Rev Respir Dis. 1975 Apr;111(4):389-97. doi: 10.1164/arrd.1975.111.4.389.
Pulmonary function studies were performed in 28 asymptomatic adolescents with idiopathic scoliosis. Tests included spirometry, flow volume curve, measurements of inspired gas distribution, diffusing capacity, closing volume, ventilatory response to carbon dioxide, and arterial blood gas analysis. In addition to the well-known decreases in lung volumes, a reduction in diffusing capacity, arterial oxygen tension, and ventilatory response to carbon dioxide were also documented. Significant correlations existed between the severity of the spinal curvature and the decrease in lung volumes. A significant correlation was also found between the degree of hypoxemia and the reduction in the diffusing capacity, suggesting that a low diffusing could be the cause of the observed arterial hypoxemia.
对28名无症状的特发性脊柱侧凸青少年进行了肺功能研究。测试包括肺活量测定、流量容积曲线、吸入气体分布测量、弥散能力、闭合气量、对二氧化碳的通气反应以及动脉血气分析。除了众所周知的肺容积减少外，还记录到弥散能力、动脉血氧张力和对二氧化碳的通气反应降低。脊柱侧弯的严重程度与肺容积减少之间存在显著相关性。低氧血症程度与弥散能力降低之间也发现了显著相关性，这表明低弥散能力可能是观察到的动脉低氧血症的原因。
