Chemical and Clinical Laboratory, ASL 1, Carrara, Italy.
Epidemiol Infect. 2013 Oct;141(10):2192-5. doi: 10.1017/S0950268812002841. Epub 2012 Dec 11.
This study aimed to estimate possible changes in seroprevalence of anti-Toxoplasma gondii IgG and IgM antibodies in people living in the area of Massa and Carrara (central Italy), in recent years. Serum samples from over 13 000 individuals were tested for both IgG and IgM anti- Toxoplasma antibodies using an immunoenzymatic method (Access® Toxo IgG, and Access® Toxo IgM II, Beckman Coulter Inc., USA). Our survey showed a decreasing trend of overall seroprevalence of 24.4% [95% confidence interval (CI) 22.62–25.71] in 2010 compared to 31.0% (95% CI 29.29–32.72) in 2007. A positive trend according to age was found, with low positivity observed in younger age groups. For women of reproductive age the prevalence of IgG antibodies was 30.2% (95% CI 28.44–31.96) in 2007 and 23.6% (95% CI 22.05–25.20) in 2010. IgM seroprevalence in women of this age group also progressively decreased from 1.6% to 0.97% during the study period. Our study confirms a decline of toxoplasmosis in Western countries.
本研究旨在评估近年来生活在意大年夜利中部马萨和卡拉拉地区人群中抗弓形虫 IgG 和 IgM 抗体的血清风行率可能发生的变更。应用免疫酶方法（Access® Toxo IgG 和 Access® Toxo IgM II，贝克曼库尔特公司，美国）对跨越 13000 例血清样本同时检测 IgG 和 IgM 抗弓形虫抗体。我们的查询拜访显示，2010 年总体风行率为 24.4%（95%CI 22.62-25.71），比拟 2007 年的 31.0%（95%CI 29.29-32.72）出现降低趋势。按照年纪不雅察到了一个积极的趋势，年纪较小的群体阳性率较低。2007 年，育龄妇女 IgG 抗体风行率为 30.2%（95%CI 28.44-31.96），2010 年为 23.6%（95%CI 22.05-25.20）。在研究时代，该年纪组妇女的 IgM 血清风行率也从 1.6%慢慢降低至 0.97%。我们的研究确认了西方国度弓形体病风行率的降低。
