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2017-2021 年巴勒斯坦西岸地区患者弓形虫感染的血清流行率和分布。

Seroprevalence and Distribution of Toxoplasma gondii Infections among Patients in the West Bank, Palestine (2017-2021).

机构信息

Faculty of Health Professions, Al-Quds University, Abu Dis, Palestine.

School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.

出版信息

Am J Trop Med Hyg. 2024 Sep 17;111(5):1000-1004. doi: 10.4269/ajtmh.23-0721. Print 2024 Nov 6.

Abstract

Toxoplasmosis is a zoonotic disease caused by the obligate intracellular protozoan Toxoplasma gondii. The current study assessed the seroepidemiological status and risk factors of T. gondii in the West Bank, Palestine. We conducted a retrospective study among 1,475 patients referred for serological examination for toxoplasmosis between 2017 and 2021 at the Central Public Health Laboratory. The overall prevalences of anti-T. gondii IgG and IgM antibodies were 1.0% [18.9-23.0%] and 1.0% [0.5-1.6%], respectively. Multifactorial analysis showed that age and sex were significantly associated with the presence of IgG antibodies. The prevalence of IgG antibodies was highest in 2018 and decreased significantly each year until 2021. Routine serological screening in women of childbearing age and pregnant women is recommended.

摘要

弓形虫病是一种由专性细胞内原生动物弓形虫引起的人畜共患病。本研究评估了巴勒斯坦西岸弓形虫的血清流行病学状况和危险因素。我们对 2017 年至 2021 年期间在中央公共卫生实验室因弓形虫病进行血清学检查的 1475 名患者进行了回顾性研究。抗弓形虫 IgG 和 IgM 抗体的总流行率分别为 1.0%[18.9-23.0%]和 1.0%[0.5-1.6%]。多因素分析显示,年龄和性别与 IgG 抗体的存在显著相关。2018 年 IgG 抗体的流行率最高,此后每年显著下降,直到 2021 年。建议对育龄妇女和孕妇进行常规血清学筛查。

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