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在巴西巴拉那州卡斯卡韦尔市风湿病科确诊的类风湿性关节炎患者的临床和实验室特征。

Clinical and laboratory features of patients with rheumatoid arthritis diagnosed at rheumatology services in the Brazilian municipality of Cascavel, PR, Brazil.

作者信息

David Juliano Maximiano, Mattei Rodrigo Antonio, Mauad Juliana Lustoza, de Almeida Lauren Gabrielle, Nogueira Márcio Augusto, Menolli Poliana Vieira da Silva, Menolli Rafael Andrade

机构信息

Universidade Estadual do Oeste do Paraná, Brazil.

出版信息

Rev Bras Reumatol. 2013 Feb;53(1):57-65. doi: 10.1016/s2255-5021(13)70006-3.

Abstract

INTRODUCTION

Brazilian epidemiological studies on rheumatoid arthritis are scarce, thus all data currently available originate from the international literature.

OBJECTIVES

To determine the incidence and some clinical and laboratory characteristics of patients with rheumatoid arthritis in the municipality of Cascavel, state of Paraná, Brazil.

PATIENTS AND METHODS

Data were collected between August 2010 and July 2011 in all health services of the municipality of Cascavel that provided health care in Rheumatology: a university-affiliated hospital, a public outpatient clinic and four private clinics.

RESULTS

We identified 38 patients diagnosed with rheumatoid arthritis, resulting in an estimated incidence of 13.4 cases per 100,000 inhabitants/year. Thirty two patients were females, whose mean age was 47.6 years. The age group with the highest incidence was over 40 years. The mean time between first symptoms and diagnosis was 12.4 months. Rheumatoid factor was positive in 68.4% of the patients, and 18.4% already had radiological abnormalities at diagnosis. The pharmacological treatment of patients was also assessed and proved to be in accordance with those found in the literature.

CONCLUSION

The incidence of rheumatoid arthritis obtained in the municipality of Cascavel was lower than those reported in international studies.

摘要

引言

巴西关于类风湿关节炎的流行病学研究较少,因此目前所有可得数据均源自国际文献。

目的

确定巴西巴拉那州卡斯卡韦尔市类风湿关节炎患者的发病率以及一些临床和实验室特征。

患者与方法

于2010年8月至2011年7月期间,在卡斯卡韦尔市所有提供风湿病医疗服务的医疗机构收集数据,这些机构包括一家大学附属医院、一家公立门诊诊所和四家私人诊所。

结果

我们识别出38例被诊断为类风湿关节炎的患者,估计发病率为每10万居民/年13.4例。32例为女性,平均年龄为47.6岁。发病率最高的年龄组为40岁以上。首次出现症状至诊断的平均时间为12.4个月。68.4%的患者类风湿因子呈阳性,18.4%的患者在诊断时已有放射学异常。还对患者的药物治疗进行了评估,结果证明与文献中所发现的情况相符。

结论

卡斯卡韦尔市获得的类风湿关节炎发病率低于国际研究报告的发病率。

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