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意大利中部内陆地区类风湿关节炎、银屑病关节炎和风湿性多肌痛的发病率:CAMPO-RHE研究结果

Incidence of rheumatoid arthritis, psoriatic arthritis and polymyalgia rheumatica in an inland area of central Italy: results of the CAMPO-RHE study.

作者信息

De Socio Antonia, Perrotta Fabio Massimo, Grasso Guido Maria, Lubrano Ennio

机构信息

a Academic Rheumatology Unit, Dipartimento di Medicina e Scienze della Salute "Vincenzo Tiberio" , Università degli Studi del Molise , Campobasso , Italy.

b Hygiene and Epidemiology, Dipartimento di Medicina e Scienze della Salute "Vincenzo Tiberio" , Università degli Studi del Molise , Campobasso , Italy.

出版信息

Postgrad Med. 2018 Jan;130(1):137-141. doi: 10.1080/00325481.2018.1399774. Epub 2017 Nov 3.

Abstract

OBJECTIVE

The aim of the CAMPO-RHE study was to determine the incidence of rheumatoid arthritis (RA), psoriatic arthritis (PsA) and polymyalgia rheumatica (PMR) in patients attending a rheumatologic outpatient's clinic of a new institution in Campobasso, Italy.

METHODS

Campobasso is a small town of approximately 50,000 inhabitants located in the inland territory of central Italy (Molise), and Public Health is managed from a single health authority. In Italy, all citizens are registered with a National Health System of General Practitioner (GP) Physicians. Between the 1 of June 2014 and the 31 of May 2016, all consecutive adult patients, sent by a GP, of Campobasso with any diagnosis of musculoskeletal symptoms/signs/complaints were evaluated in a single rheumatology outpatient clinic of our Academic Unit. The clinic represents the first and unique reference for GPs about rheumatic diseases in the territory. Subjects were classified using the 2010 EULAR criteria for RA, the CASPAR criteria for PsA and the 2012 ACR classification criteria for PMR.

RESULTS

1003 adult patients, sent by GPs, with articular or musculoskeletal complaints visited our clinic. Of these, 409 inhabitants of the municipality of Campobasso were evaluated for the study. During the 2-year study period we diagnosed 18, 19 and 12 new cases of RA, PsA and PMR respectively, with a new incident cases rate of 21.4, 22.59 and 27.43/100,000/year on the population at risk.

CONCLUSION

The results of our study could contribute to better define the incidence of these rheumatic diseases classified with the new classification criteria.

摘要

目的

CAMPO - RHE研究的目的是确定在意大利坎波巴索一家新机构的风湿病门诊就诊的患者中类风湿关节炎(RA)、银屑病关节炎(PsA)和风湿性多肌痛(PMR)的发病率。

方法

坎波巴索是意大利中部内陆地区(莫利塞)一个约有5万居民的小镇,公共卫生由单一卫生当局管理。在意大利,所有公民都在国家全科医生(GP)医疗系统中注册。2014年6月1日至2016年5月31日期间,我们学术单位的单一风湿病门诊对所有由全科医生送来的、有任何肌肉骨骼症状/体征/主诉诊断的连续成年坎波巴索患者进行了评估。该门诊是该地区全科医生关于风湿性疾病的首个也是唯一的参考机构。根据2010年欧洲抗风湿病联盟(EULAR)类风湿关节炎标准、银屑病关节炎分类标准(CASPAR)和2012年美国风湿病学会(ACR)风湿性多肌痛分类标准对受试者进行分类。

结果

1003名由全科医生送来的、有关节或肌肉骨骼主诉的成年患者前来我们门诊就诊。其中,对坎波巴索市的409名居民进行了研究评估。在为期2年的研究期间,我们分别诊断出18例、19例和12例新的类风湿关节炎、银屑病关节炎和风湿性多肌痛病例,高危人群中新发病例率分别为每年21.4/10万、22.59/10万和27.43/10万。

结论

我们的研究结果有助于更好地确定这些采用新分类标准分类的风湿性疾病的发病率。

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